Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   G7052_RS03215 Genome accession   NZ_CP049799
Coordinates   641150..641584 (+) Length   144 a.a.
NCBI ID   WP_023612536.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1040     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 636150..646584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7052_RS03185 (G7052_03185) - 637819..638184 (+) 366 WP_002986560.1 DUF1033 family protein -
  G7052_RS03190 (G7052_03190) comYA 638277..639215 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  G7052_RS03195 (G7052_03195) comYB 639151..640185 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  G7052_RS03200 (G7052_03200) comYC 640187..640513 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  G7052_RS03205 (G7052_03205) comGD 640488..640916 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  G7052_RS03210 (G7052_03210) comGE 640873..641157 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  G7052_RS03215 (G7052_03215) comYF 641150..641584 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  G7052_RS03220 (G7052_03220) comGG 641568..641894 (+) 327 WP_136274078.1 competence type IV pilus minor pilin ComGG -
  G7052_RS03225 (G7052_03225) comYH 641992..642945 (+) 954 WP_136274080.1 class I SAM-dependent methyltransferase Machinery gene
  G7052_RS03230 (G7052_03230) - 643004..644200 (+) 1197 WP_023612537.1 acetate kinase -
  G7052_RS03235 (G7052_03235) - 644387..644695 (+) 309 WP_010921804.1 hypothetical protein -
  G7052_RS03240 (G7052_03240) proC 644778..645548 (-) 771 WP_136274084.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16688.29 Da        Isoelectric Point: 10.2526

>NTDB_id=427865 G7052_RS03215 WP_023612536.1 641150..641584(+) (comYF) [Streptococcus pyogenes strain 1040]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=427865 G7052_RS03215 WP_023612536.1 641150..641584(+) (comYF) [Streptococcus pyogenes strain 1040]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

50.36

96.528

0.486
  comYF Streptococcus mutans UA159

49.64

96.528

0.479
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

43.284

93.056

0.403
  comGF/cglF Streptococcus pneumoniae Rx1

42.105

92.361

0.389
  comGF/cglF Streptococcus pneumoniae D39

42.105

92.361

0.389
  comGF/cglF Streptococcus pneumoniae R6

42.105

92.361

0.389
  comGF/cglF Streptococcus pneumoniae TIGR4

42.105

92.361

0.389
  comGF/cglF Streptococcus mitis SK321

41.353

92.361

0.382