Detailed information NTG0426823

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: G8B43_RS07615
• Genome accession: NZ_CP049689
• Coordinates: 1494519..1495520 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain ABC221
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1489519..1500520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G8B43_RS07600 (G8B43_07640)	thrS	1489689..1491632 (-)	1944	WP_011528363.1	threonine--tRNA ligase	-
G8B43_RS07605 (G8B43_07645)	-	1492054..1493388 (-)	1335	WP_011528362.1	glycosyltransferase family 4 protein	-
G8B43_RS07610 (G8B43_07650)	-	1493390..1494388 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
G8B43_RS07615 (G8B43_07655)	ccpA	1494519..1495520 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
G8B43_RS07620 (G8B43_07660)	-	1495694..1496779 (+)	1086	WP_011528361.1	aminopeptidase P family protein	-
G8B43_RS07625 (G8B43_07665)	-	1496828..1497493 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
G8B43_RS07630 (G8B43_07670)	-	1497504..1497881 (+)	378	WP_002985686.1	VOC family protein	-
G8B43_RS07635 (G8B43_07675)	-	1498026..1498952 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
G8B43_RS07640 (G8B43_07680)	-	1499163..1499846 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=426823 G8B43_RS07615 WP_002985680.1 1494519..1495520(-) (ccpA) [Streptococcus pyogenes strain ABC221]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=426823 G8B43_RS07615 WP_002985680.1 1494519..1495520(-) (ccpA) [Streptococcus pyogenes strain ABC221]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559