Detailed information NTG0425292

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: G6Z52_RS04605
• Genome accession: NZ_CP049187
• Coordinates: 927058..928368 (-)
• Length: 436 a.a.
• NCBI ID: WP_002989693.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1687
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 922058..933368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G6Z52_RS04580 (G6Z52_04605)	-	922664..923716 (-)	1053	WP_002989701.1	BMP family protein	-
G6Z52_RS04585 (G6Z52_04610)	-	923810..924199 (-)	390	WP_002984531.1	cytidine deaminase	-
G6Z52_RS04590 (G6Z52_04615)	-	924850..925443 (-)	594	WP_002989699.1	class I SAM-dependent methyltransferase	-
G6Z52_RS04595 (G6Z52_04620)	coaA	925711..926631 (+)	921	WP_002989697.1	type I pantothenate kinase	-
G6Z52_RS04600 (G6Z52_04625)	rpsT	926685..926933 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
G6Z52_RS04605 (G6Z52_04630)	ciaH	927058..928368 (-)	1311	WP_002989693.1	HAMP domain-containing sensor histidine kinase	Regulator
G6Z52_RS04610 (G6Z52_04635)	ciaR	928361..929035 (-)	675	WP_002984519.1	response regulator transcription factor	Regulator
G6Z52_RS04615 (G6Z52_04640)	-	929381..931918 (-)	2538	WP_002989692.1	M1 family metallopeptidase	-
G6Z52_RS04620 (G6Z52_04645)	phoU	932123..932776 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50119.65 Da
• Isoelectric Point: 9.0641

>NTDB_id=425292 G6Z52_RS04605 WP_002989693.1 927058..928368(-) (ciaH) [Streptococcus pyogenes strain TSPY1687]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKYRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=425292 G6Z52_RS04605 WP_002989693.1 927058..928368(-) (ciaH) [Streptococcus pyogenes strain TSPY1687]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAATACCGTTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAACTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.895	100	0.58
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516