Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   IHN52_RS17010 Genome accession   NZ_CP062243
Coordinates   3479479..3480111 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AML003_ev03     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3474479..3485111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IHN52_RS16985 yheS 3474648..3476561 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  IHN52_RS16990 yheT 3476561..3477583 (+) 1023 WP_000057356.1 hydrolase -
  IHN52_RS16995 yheU 3477577..3477795 (+) 219 WP_000907085.1 YheU family protein -
  IHN52_RS17000 prkB 3477849..3478718 (+) 870 WP_001274680.1 phosphoribulokinase -
  IHN52_RS17005 yhfA 3478773..3479177 (-) 405 WP_001148908.1 OsmC family protein -
  IHN52_RS17010 crp 3479479..3480111 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  IHN52_RS17015 yhfK 3480162..3482252 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  IHN52_RS17020 argD 3482319..3483539 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  IHN52_RS17025 pabA 3483625..3484188 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  IHN52_RS17030 fic 3484220..3484822 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  IHN52_RS17035 yhfG 3484812..3484979 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=424714 IHN52_RS17010 WP_000242755.1 3479479..3480111(+) (crp) [Escherichia coli strain AML003_ev03]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=424714 IHN52_RS17010 WP_000242755.1 3479479..3480111(+) (crp) [Escherichia coli strain AML003_ev03]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467