Detailed information NTG0424472

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST64987_RS03195
• Genome accession: NZ_CP049053
• Coordinates: 587266..588267 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain ST64987
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 582266..593267

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS03175 (ST64987_0582)	smpB	583371..583835 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST64987_RS03180 (ST64987_0583)	-	583989..585395 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
ST64987_RS03185 (ST64987_0584)	-	585397..585762 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST64987_RS03190 (ST64987_0585)	-	585865..586950 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
ST64987_RS03195 (ST64987_0586)	ccpA	587266..588267 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST64987_RS03200 (ST64987_0587)	-	588327..588494 (+)	168	WP_014621359.1	hypothetical protein	-
ST64987_RS03205 (ST64987_0588)	-	588630..589394 (+)	765	WP_014621361.1	MmcQ/YjbR family DNA-binding protein	-
ST64987_RS03210 (ST64987_0589)	-	589407..590522 (+)	1116	WP_011680937.1	glycerate kinase	-
ST64987_RS03215 (ST64987_0590)	-	590569..591024 (-)	456	WP_011680938.1	YueI family protein	-
ST64987_RS03220 (ST64987_0591)	eno	591233..592537 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
ST64987_RS03225	-	592689..592873 (-)	185	Protein_563	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=424472 ST64987_RS03195 WP_004197422.1 587266..588267(+) (ccpA) [Streptococcus thermophilus strain ST64987]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=424472 ST64987_RS03195 WP_004197422.1 587266..588267(+) (ccpA) [Streptococcus thermophilus strain ST64987]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGATGTT
ATCCTTAATCATGGTCTAACTTTACGCCAATCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547