Detailed information NTG0422307

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: IEC99_RS03780
• Genome accession: NZ_CP061754
• Coordinates: 778451..779110 (-)
• Length: 219 a.a.
• NCBI ID: WP_191028008.1
• Uniprot ID: -
• Organism: Escherichia coli O18ac:H14 strain 873.10
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 773451..784110

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IEC99_RS03755 (IEC99_03755)	ygiN	774352..774666 (-)	315	WP_000958598.1	putative quinol monooxygenase	-
IEC99_RS03760 (IEC99_03760)	mdaB	774697..775278 (-)	582	WP_000065430.1	NADPH:quinone oxidoreductase MdaB	-
IEC99_RS26230	-	775528..776007 (+)	480	WP_225880103.1	Hcp family type VI secretion system effector	-
IEC99_RS26235	-	776010..776720 (+)	711	WP_225880102.1	hypothetical protein	-
IEC99_RS03770 (IEC99_03770)	ygiZ	776727..777059 (+)	333	WP_000914691.1	DUF2645 family protein	-
IEC99_RS03775 (IEC99_03775)	qseC	777105..778454 (-)	1350	WP_000673354.1	quorum sensing histidine kinase QseC	-
IEC99_RS03780 (IEC99_03780)	ciaR	778451..779110 (-)	660	WP_191028008.1	quorum sensing response regulator transcription factor QseB	Regulator
IEC99_RS03785 (IEC99_03785)	ygiW	779262..779654 (+)	393	WP_000712658.1	OB fold stress tolerance protein YgiW	-
IEC99_RS03790 (IEC99_03790)	ygiV	779707..780189 (+)	483	WP_000183494.1	AraC family transcriptional regulator	-
IEC99_RS03795 (IEC99_03795)	mqsR	780394..780690 (+)	297	WP_000415584.1	type II toxin-antitoxin system toxin MqsR	-
IEC99_RS03800 (IEC99_03800)	mqsA	780692..781087 (+)	396	WP_000650107.1	type II toxin-antitoxin system antitoxin MqsA	-
IEC99_RS03805 (IEC99_03805)	ygiS	781220..782668 (+)	1449	WP_191028007.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24773.72 Da
• Isoelectric Point: 6.6543

>NTDB_id=422307 IEC99_RS03780 WP_191028008.1 778451..779110(-) (ciaR) [Escherichia coli O18ac:H14 strain 873.10]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQVSNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide

• Length: 660 bp

>NTDB_id=422307 IEC99_RS03780 WP_191028008.1 778451..779110(-) (ciaR) [Escherichia coli O18ac:H14 strain 873.10]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGTCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-216)

• Response regulator receiver domain (Response_reg) (3-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.326	100	0.397
ciaR	Streptococcus pneumoniae D39	38.326	100	0.397
ciaR	Streptococcus pneumoniae R6	38.326	100	0.397
ciaR	Streptococcus pneumoniae TIGR4	38.326	100	0.397
ciaR	Streptococcus mutans UA159	35.874	100	0.365