Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IED00_RS09955 Genome accession   NZ_CP061749
Coordinates   2076437..2077093 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O15:H12 strain 2273-PO3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071437..2082093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IED00_RS09925 (IED00_09925) dcyD 2072317..2073303 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IED00_RS09930 (IED00_09930) tcyL 2073318..2073986 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IED00_RS09935 (IED00_09935) tcyN 2073983..2074735 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IED00_RS09940 (IED00_09940) sdiA 2074965..2075687 (+) 723 Protein_1966 transcriptional regulator SdiA -
  IED00_RS09945 (IED00_09945) yecF 2075754..2075978 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IED00_RS09950 (IED00_09950) yecU 2075965..2076141 (-) 177 WP_000590347.1 protein YecU -
  IED00_RS26350 - 2076224..2076295 (-) 72 Protein_1969 transcriptional regulator -
  IED00_RS09955 (IED00_09955) letA 2076437..2077093 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IED00_RS09960 (IED00_09960) uvrC 2077090..2078922 (+) 1833 WP_016240020.1 excinuclease ABC subunit UvrC Machinery gene
  IED00_RS09965 (IED00_09965) pgsA 2078979..2079527 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IED00_RS09985 (IED00_09985) - 2080235..2080978 (-) 744 WP_042201988.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=422243 IED00_RS09955 WP_000611335.1 2076437..2077093(+) (letA) [Escherichia coli O15:H12 strain 2273-PO3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=422243 IED00_RS09955 WP_000611335.1 2076437..2077093(+) (letA) [Escherichia coli O15:H12 strain 2273-PO3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment