Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   PARA_RS00335 Genome accession   NC_015964
Coordinates   64448..65116 (-) Length   222 a.a.
NCBI ID   WP_014064026.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae T3T1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 59448..70116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PARA_RS00315 (PARA_00650) - 59746..60612 (-) 867 WP_014064022.1 MurR/RpiR family transcriptional regulator -
  PARA_RS00320 (PARA_00660) - 60605..61543 (-) 939 WP_014064023.1 N-acetylmannosamine kinase -
  PARA_RS00325 (PARA_00670) - 61555..62244 (-) 690 WP_014064024.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  PARA_RS00330 (PARA_00680) nagE 62472..63938 (+) 1467 WP_014064025.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  PARA_RS00335 (PARA_00690) crp 64448..65116 (-) 669 WP_014064026.1 cAMP-activated global transcriptional regulator CRP Regulator
  PARA_RS00340 (PARA_00700) - 65133..65351 (-) 219 WP_014064027.1 YheU family protein -
  PARA_RS00345 (PARA_00710) slmA 65373..66026 (-) 654 WP_005698358.1 nucleoid occlusion factor SlmA -
  PARA_RS00350 (PARA_00720) dut 66030..66485 (-) 456 WP_005698440.1 dUTP diphosphatase -
  PARA_RS00355 (PARA_00730) coaBC 66558..67760 (-) 1203 WP_014064028.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  PARA_RS00360 (PARA_00740) radC 67962..68627 (+) 666 WP_014064029.1 RadC family protein -
  PARA_RS00365 (PARA_00750) rpmB 68846..69082 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  PARA_RS00370 (PARA_00760) rpmG 69094..69264 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25163.95 Da        Isoelectric Point: 6.6936

>NTDB_id=42223 PARA_RS00335 WP_014064026.1 64448..65116(-) (crp) [Haemophilus parainfluenzae T3T1]
MSEDVELLEEQKLQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=42223 PARA_RS00335 WP_014064026.1 64448..65116(-) (crp) [Haemophilus parainfluenzae T3T1]
ATGTCAGAAGATGTAGAATTACTTGAAGAACAAAAGTTACAAGACGATGATCAGCAGCGCGATCCTGCTCTGGATTGGTT
CCTAACTCACTGTCATTTGCATAAATATCCTGCAAAATCGACCTTAATACATGCAGGGGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACCGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCCGGA
CAATTTTTTGGTGAGGCAGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTGAAAACGAAAACCCCTTGTGAAAT
TGCGGAAATTTCCTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAACGTTTGCAAAACACGTCTCGACAAGTGACTAACCTGGCCTTTTTAGATGTGGCAGGGCGTATTGCTCAGGCGCTT
ATGCATCTAGCAAAACAACCTGAAGCTATGACTCATCCTGATGGTATGCAGATTAAAATTACGCGTCAGGAAATCGGTCA
AATGGTGGGCTGTTCACGTGAAACCGTAGGGCGAATAATTAAGATGCTGGAAGATCAGAATCTCATTCATGCGCACGGCA
AAACCATTGTTGTTTACGGCACTCGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414

Multiple sequence alignment