Detailed information NTG0421666

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: G3M69_RS01635
• Genome accession: NZ_CP048599
• Coordinates: 343256..344056 (+)
• Length: 266 a.a.
• NCBI ID: WP_000835215.1
• Uniprot ID: I9U7J7
• Organism: Helicobacter pylori strain GCT 97
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 338256..349056

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G3M69_RS01600 (G3M69_01600)	pseH	338756..339298 (+)	543	WP_163562826.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
G3M69_RS01605 (G3M69_01605)	-	339231..340169 (-)	939	WP_163562827.1	tetraacyldisaccharide 4'-kinase	-
G3M69_RS01610 (G3M69_01610)	-	340166..340948 (-)	783	WP_163562828.1	NAD+ synthase	-
G3M69_RS01620 (G3M69_01620)	ilvC	341197..342189 (+)	993	WP_163562829.1	ketol-acid reductoisomerase	-
G3M69_RS01625 (G3M69_01625)	minD	342213..343019 (+)	807	WP_001019048.1	septum site-determining protein MinD	-
G3M69_RS01630 (G3M69_01630)	minE	343016..343249 (+)	234	WP_000051414.1	cell division topological specificity factor MinE	-
G3M69_RS01635 (G3M69_01635)	dprA	343256..344056 (+)	801	WP_000835215.1	DNA-processing protein DprA	Machinery gene
G3M69_RS01640 (G3M69_01640)	dprB	344053..344457 (+)	405	WP_163562830.1	Holliday junction resolvase RuvX	Machinery gene
G3M69_RS01645 (G3M69_01645)	-	344743..344993 (+)	251	Protein_326	sel1 repeat family protein	-
G3M69_RS01650 (G3M69_01650)	-	345179..345517 (+)	339	WP_000699883.1	hypothetical protein	-
G3M69_RS01655 (G3M69_01655)	-	345501..346061 (+)	561	WP_163562831.1	hypothetical protein	-
G3M69_RS01660 (G3M69_01660)	-	346164..347045 (-)	882	WP_163562832.1	RluA family pseudouridine synthase	-
G3M69_RS01665 (G3M69_01665)	recJ	347045..348595 (-)	1551	WP_163562833.1	single-stranded-DNA-specific exonuclease RecJ	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29839.77 Da
• Isoelectric Point: 8.5952

>NTDB_id=421666 G3M69_RS01635 WP_000835215.1 343256..344056(+) (dprA) [Helicobacter pylori strain GCT 97]
MKSHFQYSALENIPKAFDILKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDHHLKEMPEMKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHLVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=421666 G3M69_RS01635 WP_000835215.1 343256..344056(+) (dprA) [Helicobacter pylori strain GCT 97]
ATGAAAAGCCATTTCCAATACAGCGCGCTAGAAAATATCCCTAAAGCCTTTGACATTCTCAAAGACCCCCCTAAAAAACT
CTATTGTGTGGGCGATACTAAGCTTTTGGAAGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTACA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTGCCAAAAACGATCATGCTTTCGCCTTGCAGTTTGGATTTCATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTCATGCCCATTAAAG
GCTCTTTTTTAGCGAGAAACCGCCTAGTGATCGCTTTAAGCGATGCGGTCATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCTCAAAAATACCAAAAACCCTTATTCGTTTTGCCCCAGCGCTTAAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGATC
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTGCGCGAAAAACCCGAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATCAAGCGCATCAATCATCTCGTGGTGTTAGCATG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (12-197)

3D structure

• AlphaFold DB: I9U7J7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	97.368	100	0.974
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414