Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZH82_RS04970 Genome accession   NZ_CP048279
Coordinates   1124592..1125221 (+) Length   209 a.a.
NCBI ID   WP_014613482.1    Uniprot ID   -
Organism   Staphylococcus sp. MI 10-1553     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1119592..1130221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZH82_RS14510 - 1119751..1119855 (-) 105 WP_343236285.1 ATP-binding protein -
  GZH82_RS04945 (GZH82_04945) - 1120504..1121502 (-) 999 WP_162681564.1 aromatic acid exporter family protein -
  GZH82_RS04950 (GZH82_04950) map 1121600..1122361 (+) 762 WP_162681565.1 type I methionyl aminopeptidase -
  GZH82_RS04955 (GZH82_04955) - 1122459..1122848 (+) 390 WP_162681566.1 hypothetical protein -
  GZH82_RS04960 (GZH82_04960) liaF 1122861..1123562 (+) 702 WP_162681567.1 cell wall-active antibiotics response protein LiaF -
  GZH82_RS04965 (GZH82_04965) vraS 1123559..1124602 (+) 1044 WP_162681568.1 sensor histidine kinase Regulator
  GZH82_RS04970 (GZH82_04970) vraR 1124592..1125221 (+) 630 WP_014613482.1 response regulator transcription factor Regulator
  GZH82_RS04975 (GZH82_04975) - 1125276..1125857 (-) 582 WP_162681569.1 carbonic anhydrase -
  GZH82_RS04980 (GZH82_04980) - 1125890..1127236 (-) 1347 WP_162681570.1 YihY/virulence factor BrkB family protein -
  GZH82_RS04985 (GZH82_04985) - 1127453..1127740 (-) 288 WP_014613485.1 YtxH domain-containing protein -
  GZH82_RS04990 (GZH82_04990) - 1127748..1128206 (-) 459 WP_162681571.1 low molecular weight protein-tyrosine-phosphatase -
  GZH82_RS04995 (GZH82_04995) - 1128339..1128542 (+) 204 WP_162681572.1 DUF1128 family protein -
  GZH82_RS05000 (GZH82_05000) - 1128564..1129796 (+) 1233 WP_162681573.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23484.17 Da        Isoelectric Point: 5.1671

>NTDB_id=420544 GZH82_RS04970 WP_014613482.1 1124592..1125221(+) (vraR) [Staphylococcus sp. MI 10-1553]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIAKAHELKPDLILMDLVMTDMDGVEATMQIKKDLPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSANDIAEAVRKTSRGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=420544 GZH82_RS04970 WP_014613482.1 1124592..1125221(+) (vraR) [Staphylococcus sp. MI 10-1553]
ATGACAATTAAAGTATTATTTGTTGATGATCATGAAATGGTACGTATAGGGATTTCAAGTTATTTATCAACACAACCCGA
TATCGAAGTTGTGGGGGAAGGCGCCTCAGGTAAAGAAGCGATCGCAAAAGCCCACGAACTCAAGCCTGACTTAATTTTAA
TGGATTTAGTGATGACTGATATGGACGGCGTTGAAGCGACAATGCAAATTAAGAAAGATTTGCCACATATTAAAGTCGTG
ATGCTGACAAGTTATATTGAAGATAAAGAAGTGTATCGTGCATTAGATGCCGGTGTAGATAGTTATATTTTAAAAACGAC
AAGTGCAAATGATATTGCGGAAGCAGTACGTAAAACGAGTCGTGGTGAGTCTGTATTTGAAGCGGAAGTATTAGTGAAAA
TGCGCAATCGAATGAAGCAACGCGCGGAGTTATATGAGTTGTTGACTGAGCGTGAGATGGAAATTTTATTATTGATTTCA
AAAGGCTATTCGAACCAAGAGATTGCAAGTGCGTCACATATTACGATTAAGACGGTGAAGACGCATGTGAGTAATATTTT
AAGTAAGCTTGAGGTGCAGGATCGTACGCAAGCGGTCATTTATGCTTTCCAACACGGCTTGATTGAGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

92.823

100

0.928
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment