Detailed information NTG0420543

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IB935_RS05670
• Genome accession: NZ_CP061134
• Coordinates: 1141685..1142647 (-)
• Length: 320 a.a.
• NCBI ID: WP_002983995.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1136685..1147647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IB935_RS05655 (IB935_05655)	-	1137522..1138229 (-)	708	WP_011528760.1	O-methyltransferase	-
IB935_RS05660 (IB935_05660)	-	1138295..1139491 (-)	1197	WP_002995765.1	OFA family MFS transporter	-
IB935_RS05665 (IB935_05665)	pepF	1139867..1141672 (-)	1806	WP_002995768.1	oligoendopeptidase F	Regulator
IB935_RS05670 (IB935_05670)	coiA	1141685..1142647 (-)	963	WP_002983995.1	competence protein CoiA	Machinery gene
IB935_RS05675 (IB935_05675)	-	1142942..1143658 (-)	717	WP_011528761.1	pseudouridine synthase	-
IB935_RS05680 (IB935_05680)	nagB	1143777..1144481 (-)	705	WP_021299319.1	glucosamine-6-phosphate deaminase	-
IB935_RS05685 (IB935_05685)	queA	1144683..1145711 (+)	1029	WP_011528763.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
IB935_RS05690 (IB935_05690)	-	1145718..1146938 (+)	1221	WP_011528764.1	DUF3114 domain-containing protein	-

Sequence

Protein

• Length: 320 a.a.
• Molecular weight: 37801.25 Da
• Isoelectric Point: 10.2848

>NTDB_id=420543 IB935_RS05670 WP_002983995.1 1141685..1142647(-) (coiA) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide

• Length: 963 bp

>NTDB_id=420543 IB935_RS05670 WP_002983995.1 1141685..1142647(-) (coiA) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTTTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCATTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (19-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	42.903	96.875	0.416
coiA	Streptococcus pneumoniae Rx1	41.613	96.875	0.403
coiA	Streptococcus pneumoniae D39	41.613	96.875	0.403
coiA	Streptococcus pneumoniae R6	41.613	96.875	0.403
coiA	Streptococcus pneumoniae TIGR4	41.613	96.875	0.403
coiA	Lactococcus lactis subsp. cremoris KW2	39.329	100	0.403