Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | GYN05_RS05810 | Genome accession | NZ_CP048250 |
| Coordinates | 1100469..1100918 (-) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain CT532 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1054581..1127343 | 1100469..1100918 | within | 0 |
Gene organization within MGE regions
Location: 1054581..1127343
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GYN05_RS05490 (GYN05_05340) | - | 1054581..1055426 (+) | 846 | WP_003690940.1 | BRO family protein | - |
| GYN05_RS05495 (GYN05_05345) | - | 1055612..1056286 (-) | 675 | WP_003687998.1 | hypothetical protein | - |
| GYN05_RS05500 (GYN05_05350) | - | 1056283..1056768 (-) | 486 | WP_003687997.1 | hypothetical protein | - |
| GYN05_RS05505 (GYN05_05355) | - | 1056774..1057247 (-) | 474 | WP_003690936.1 | hypothetical protein | - |
| GYN05_RS05510 (GYN05_05360) | - | 1057302..1058597 (-) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| GYN05_RS05515 (GYN05_05370) | - | 1059223..1066521 (-) | 7299 | WP_250328996.1 | PLxRFG domain-containing protein | - |
| GYN05_RS05520 (GYN05_05375) | - | 1066518..1067714 (-) | 1197 | WP_197098001.1 | hypothetical protein | - |
| GYN05_RS05525 | - | 1067951..1068343 (-) | 393 | WP_229690718.1 | hypothetical protein | - |
| GYN05_RS05530 (GYN05_05380) | - | 1068359..1070218 (-) | 1860 | WP_231592927.1 | hypothetical protein | - |
| GYN05_RS05535 (GYN05_05385) | - | 1070203..1071477 (-) | 1275 | WP_337999659.1 | PBSX family phage terminase large subunit | - |
| GYN05_RS05540 | - | 1071458..1071997 (-) | 540 | WP_003690920.1 | hypothetical protein | - |
| GYN05_RS05545 (GYN05_05400) | - | 1071997..1072419 (-) | 423 | WP_003690919.1 | hypothetical protein | - |
| GYN05_RS05550 (GYN05_05405) | - | 1072484..1073002 (-) | 519 | WP_003693459.1 | HNH endonuclease | - |
| GYN05_RS05555 (GYN05_05410) | - | 1072993..1073376 (-) | 384 | WP_003690918.1 | recombination protein NinB | - |
| GYN05_RS05560 (GYN05_05415) | - | 1073373..1073678 (-) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| GYN05_RS05565 (GYN05_05420) | - | 1073671..1074108 (-) | 438 | WP_017147288.1 | RusA family crossover junction endodeoxyribonuclease | - |
| GYN05_RS05570 | - | 1074099..1074380 (-) | 282 | WP_003689109.1 | hypothetical protein | - |
| GYN05_RS05575 | - | 1074409..1074558 (-) | 150 | WP_003689110.1 | hypothetical protein | - |
| GYN05_RS05580 (GYN05_05425) | - | 1074735..1075229 (-) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| GYN05_RS05585 (GYN05_05430) | - | 1075268..1075474 (-) | 207 | WP_154235857.1 | hypothetical protein | - |
| GYN05_RS05590 (GYN05_05435) | - | 1075544..1076326 (-) | 783 | WP_025456432.1 | ATP-binding protein | - |
| GYN05_RS05595 (GYN05_05440) | - | 1076342..1077382 (-) | 1041 | WP_250328954.1 | helix-turn-helix domain-containing protein | - |
| GYN05_RS05600 (GYN05_05445) | - | 1077379..1077606 (-) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| GYN05_RS05605 (GYN05_05450) | - | 1077779..1077967 (+) | 189 | WP_003706568.1 | hypothetical protein | - |
| GYN05_RS05610 | - | 1077944..1078099 (-) | 156 | WP_003691446.1 | hypothetical protein | - |
| GYN05_RS05615 (GYN05_05455) | - | 1078179..1078394 (-) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| GYN05_RS05620 (GYN05_05460) | - | 1078522..1079226 (+) | 705 | WP_050161651.1 | helix-turn-helix transcriptional regulator | - |
| GYN05_RS05625 (GYN05_05465) | - | 1079386..1079925 (+) | 540 | WP_003695998.1 | type II toxin-antitoxin system antitoxin SocA domain-containing protein | - |
| GYN05_RS05630 (GYN05_05470) | - | 1079926..1080285 (+) | 360 | WP_003691733.1 | hypothetical protein | - |
| GYN05_RS05635 (GYN05_05475) | - | 1080301..1080519 (-) | 219 | WP_003691731.1 | hypothetical protein | - |
| GYN05_RS05640 (GYN05_05480) | - | 1081003..1081203 (+) | 201 | WP_003704298.1 | hypothetical protein | - |
| GYN05_RS05645 (GYN05_05485) | - | 1081236..1081712 (+) | 477 | WP_002255718.1 | hypothetical protein | - |
| GYN05_RS05650 (GYN05_05490) | - | 1081709..1082002 (+) | 294 | WP_250328953.1 | hypothetical protein | - |
| GYN05_RS05655 (GYN05_05495) | - | 1082143..1082475 (+) | 333 | WP_003705604.1 | hypothetical protein | - |
| GYN05_RS05660 (GYN05_05500) | - | 1082628..1082903 (+) | 276 | WP_050154389.1 | hypothetical protein | - |
| GYN05_RS05665 | - | 1082900..1083061 (+) | 162 | WP_003691530.1 | hypothetical protein | - |
| GYN05_RS05670 (GYN05_05505) | - | 1083130..1083816 (+) | 687 | WP_003691532.1 | hypothetical protein | - |
| GYN05_RS05675 (GYN05_05510) | - | 1083956..1084138 (+) | 183 | WP_003691535.1 | hypothetical protein | - |
| GYN05_RS05680 (GYN05_05515) | - | 1084135..1084626 (+) | 492 | WP_218422917.1 | siphovirus Gp157 family protein | - |
| GYN05_RS05685 (GYN05_05520) | - | 1084678..1084893 (+) | 216 | WP_003691538.1 | hypothetical protein | - |
| GYN05_RS05690 (GYN05_05525) | - | 1085004..1085987 (+) | 984 | WP_047919222.1 | hypothetical protein | - |
| GYN05_RS05695 (GYN05_05530) | - | 1085984..1086397 (+) | 414 | WP_010951196.1 | hypothetical protein | - |
| GYN05_RS05700 (GYN05_05535) | - | 1086423..1086617 (+) | 195 | WP_003689159.1 | hypothetical protein | - |
| GYN05_RS05710 (GYN05_05545) | - | 1086908..1087582 (+) | 675 | WP_003689160.1 | hypothetical protein | - |
| GYN05_RS05715 (GYN05_05550) | ribA | 1087575..1088168 (+) | 594 | WP_003689161.1 | GTP cyclohydrolase II | - |
| GYN05_RS05720 (GYN05_05555) | - | 1088336..1088518 (+) | 183 | Protein_1122 | glycosyltransferase | - |
| GYN05_RS05725 (GYN05_05560) | - | 1088521..1089483 (+) | 963 | WP_250328937.1 | IS110 family transposase | - |
| GYN05_RS05730 (GYN05_05565) | - | 1090117..1090476 (-) | 360 | WP_003689732.1 | hypothetical protein | - |
| GYN05_RS05735 (GYN05_05570) | - | 1090597..1091669 (-) | 1073 | Protein_1125 | zonular occludens toxin domain-containing protein | - |
| GYN05_RS05740 (GYN05_05575) | - | 1091679..1091969 (-) | 291 | WP_047917922.1 | DUF2523 domain-containing protein | - |
| GYN05_RS05745 (GYN05_05580) | - | 1091948..1093537 (-) | 1590 | WP_202838264.1 | IgG-binding virulence factor TspB family protein | - |
| GYN05_RS05750 (GYN05_05585) | - | 1093479..1093796 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| GYN05_RS05755 (GYN05_05590) | - | 1093924..1094202 (-) | 279 | WP_003689168.1 | hypothetical protein | - |
| GYN05_RS05760 (GYN05_05595) | - | 1094209..1094428 (-) | 220 | Protein_1130 | major capsid protein | - |
| GYN05_RS05765 (GYN05_05600) | - | 1094502..1094699 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| GYN05_RS05770 (GYN05_05605) | - | 1094704..1094994 (-) | 291 | WP_012503914.1 | hypothetical protein | - |
| GYN05_RS05775 (GYN05_05610) | - | 1095039..1096390 (-) | 1352 | Protein_1133 | replication initiation factor domain-containing protein | - |
| GYN05_RS05780 (GYN05_05615) | - | 1096528..1096950 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| GYN05_RS05785 | - | 1096956..1097552 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| GYN05_RS05790 | - | 1097742..1098599 (-) | 858 | WP_012503917.1 | ATP-binding protein | - |
| GYN05_RS05795 (GYN05_05625) | - | 1098613..1099047 (-) | 435 | WP_229684538.1 | DNA cytosine methyltransferase | - |
| GYN05_RS05800 (GYN05_05630) | - | 1098981..1099571 (-) | 591 | WP_080229150.1 | DNA cytosine methyltransferase | - |
| GYN05_RS05805 | - | 1099946..1100092 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| GYN05_RS05810 (GYN05_05635) | comP | 1100469..1100918 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
| GYN05_RS05815 (GYN05_05640) | comE | 1101006..1101401 (-) | 396 | WP_003703428.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
| GYN05_RS05820 | - | 1101503..1101622 (-) | 120 | Protein_1142 | competence protein ComE | - |
| GYN05_RS05850 (GYN05_05670) | - | 1107246..1107899 (-) | 654 | Protein_1143 | TIGR01621 family pseudouridine synthase | - |
| GYN05_RS05855 (GYN05_05675) | - | 1107959..1108198 (-) | 240 | WP_229684458.1 | HAD hydrolase family protein | - |
| GYN05_RS05860 | - | 1108490..1108651 (+) | 162 | WP_003698918.1 | hypothetical protein | - |
| GYN05_RS05865 (GYN05_05685) | - | 1108671..1109324 (-) | 654 | WP_250328938.1 | IS1595 family transposase | - |
| GYN05_RS05870 (GYN05_05690) | - | 1109416..1109754 (-) | 339 | WP_002218119.1 | P-II family nitrogen regulator | - |
| GYN05_RS05875 (GYN05_05695) | purL | 1109905..1113861 (+) | 3957 | WP_250328939.1 | phosphoribosylformylglycinamidine synthase | - |
| GYN05_RS05880 (GYN05_05700) | - | 1113932..1115143 (-) | 1212 | WP_003689615.1 | NADH:flavin oxidoreductase/NADH oxidase family protein | - |
| GYN05_RS05885 (GYN05_05705) | - | 1115217..1115528 (-) | 312 | WP_003689616.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| GYN05_RS05890 (GYN05_05710) | gloB | 1115760..1116512 (+) | 753 | WP_003697499.1 | hydroxyacylglutathione hydrolase | - |
| GYN05_RS05895 (GYN05_05715) | mgtE | 1116746..1118200 (+) | 1455 | WP_003696042.1 | magnesium transporter | - |
| GYN05_RS05900 (GYN05_05720) | hslO | 1118286..1119194 (-) | 909 | WP_010360529.1 | Hsp33 family molecular chaperone HslO | - |
| GYN05_RS05905 (GYN05_05725) | - | 1119439..1120020 (+) | 582 | WP_047920185.1 | C40 family peptidase | - |
| GYN05_RS05910 (GYN05_05730) | - | 1120039..1120257 (+) | 219 | WP_003689624.1 | hypothetical protein | - |
| GYN05_RS05915 (GYN05_05735) | - | 1120402..1120746 (+) | 345 | WP_002219918.1 | CidA/LrgA family protein | - |
| GYN05_RS05920 (GYN05_05740) | - | 1120746..1121438 (+) | 693 | WP_003689629.1 | LrgB family protein | - |
| GYN05_RS05925 (GYN05_05745) | argJ | 1121505..1122725 (+) | 1221 | WP_003689631.1 | bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ | - |
| GYN05_RS05930 (GYN05_05750) | - | 1122785..1124194 (+) | 1410 | WP_050161567.1 | chloride channel protein | - |
| GYN05_RS05935 (GYN05_05755) | hrpA | 1124382..1125773 (+) | 1392 | WP_003689635.1 | ATP-dependent RNA helicase HrpA | - |
| GYN05_RS05940 (GYN05_05760) | - | 1125841..1127343 (+) | 1503 | WP_025455914.1 | SIR2 family protein | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=420193 GYN05_RS05810 WP_002214937.1 1100469..1100918(-) (comP) [Neisseria gonorrhoeae strain CT532]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=420193 GYN05_RS05810 WP_002214937.1 1100469..1100918(-) (comP) [Neisseria gonorrhoeae strain CT532]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |