Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   GWC79_RS07460 Genome accession   NZ_CP048008
Coordinates   1542135..1542851 (-) Length   238 a.a.
NCBI ID   WP_002461418.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain CGMH-SL118     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1537135..1547851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWC79_RS07440 - 1537190..1538434 (+) 1245 WP_002477917.1 ammonium transporter -
  GWC79_RS07445 - 1538534..1539484 (+) 951 WP_002461422.1 LacI family DNA-binding transcriptional regulator -
  GWC79_RS07450 - 1539584..1541068 (+) 1485 WP_002477918.1 sucrose-6-phosphate hydrolase -
  GWC79_RS07455 - 1541069..1542043 (+) 975 WP_002477919.1 carbohydrate kinase family protein -
  GWC79_RS07460 agrA 1542135..1542851 (-) 717 WP_002461418.1 quorum-sensing response regulator AgrA Regulator
  GWC79_RS07465 agrC 1542864..1544153 (-) 1290 WP_228865218.1 quorum-sensing sensor histidine kinase AgrC -
  GWC79_RS07470 agrD 1544175..1544318 (-) 144 WP_002477921.1 cyclic lactone autoinducer peptide AgrD -
  GWC79_RS07475 - 1544321..1544887 (-) 567 WP_070817133.1 accessory gene regulator AgrB -
  GWC79_RS07480 - 1545515..1546300 (-) 786 WP_002477923.1 carbon-nitrogen family hydrolase -
  GWC79_RS07485 - 1546435..1547058 (-) 624 WP_002461413.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27935.92 Da        Isoelectric Point: 5.9140

>NTDB_id=419372 GWC79_RS07460 WP_002461418.1 1542135..1542851(-) (agrA) [Staphylococcus lugdunensis strain CGMH-SL118]
MKIYICEDDVKQRENMVEIINNYIMIEEKPMEIALATDNPYEILKMSKENEDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKERTVETIELKRGSNSVYVQYDEVM
FFESSTNSHRLIAHLDNRQIEFYGNLKQISQIDDRFFRCHNSFVVNRHNISSINSKERVVYFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=419372 GWC79_RS07460 WP_002461418.1 1542135..1542851(-) (agrA) [Staphylococcus lugdunensis strain CGMH-SL118]
ATGAAGATTTACATTTGTGAAGATGATGTTAAACAACGTGAAAATATGGTTGAGATCATCAATAACTATATCATGATTGA
AGAAAAACCAATGGAAATTGCTTTAGCTACAGATAATCCTTATGAAATTTTAAAAATGTCAAAGGAAAATGAGGATGTTG
GTTGTTATTTTTTAGATATTCAATTAGAAGCTGACATAAACGGTATCAAGTTAGGTAGCGAAATAAGAAAGTATGATCCG
ATAGGTAACATAATTTTTGTTACAAGTCATAGTGAGCTGACATATTTAACTTTTGTTTACAAAGTATCGGCTATGGATTT
TATTTTTAAAGATGACCCTGCCGAACTTAAAACTCGTATTATCGATTGCCTTGAAACCGCACATACGCGCTTAAAGTTAT
TGTCAAAAGAACGTACCGTTGAAACGATAGAGCTTAAGCGCGGTAGTAATTCTGTATATGTGCAATATGATGAAGTGATG
TTTTTTGAATCATCAACAAATTCACATCGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGTAATCTAAA
ACAAATTAGTCAAATCGATGATCGTTTCTTTAGATGCCATAATAGTTTTGTTGTCAATCGACACAATATCTCTTCAATCA
ATTCAAAAGAACGTGTTGTATATTTTAAAAATGGTGAACATTGTTATGCATCAGTACGCAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.555

100

0.866

Multiple sequence alignment