Detailed information NTG0419226

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GWK37_RS06435
• Genome accession: NZ_CP048002
• Coordinates: 1274466..1275629 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain CACC 316
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1269466..1280629

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GWK37_RS06405 (GWK37_06410)	-	1269731..1270150 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
GWK37_RS06410 (GWK37_06415)	comFC	1270224..1270913 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
GWK37_RS06415 (GWK37_06420)	-	1270919..1271203 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
GWK37_RS06420 (GWK37_06425)	comFA	1271261..1272646 (-)	1386	WP_115941105.1	DEAD/DEAH box helicase	Machinery gene
GWK37_RS06425 (GWK37_06430)	-	1272754..1273602 (-)	849	WP_003151387.1	DegV family protein	-
GWK37_RS06430 (GWK37_06435)	degU	1273700..1274389 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GWK37_RS06435 (GWK37_06440)	degS	1274466..1275629 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GWK37_RS06440 (GWK37_06445)	-	1275852..1276499 (+)	648	WP_007614107.1	YigZ family protein	-
GWK37_RS06445 (GWK37_06450)	-	1276504..1277718 (+)	1215	WP_014419013.1	LCP family protein	-
GWK37_RS06450 (GWK37_06455)	-	1277817..1278893 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
GWK37_RS06455 (GWK37_06460)	tuaH	1279025..1280221 (-)	1197	WP_115941106.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=419226 GWK37_RS06435 WP_007407484.1 1274466..1275629(-) (degS) [Bacillus velezensis strain CACC 316]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=419226 GWK37_RS06435 WP_007407484.1 1274466..1275629(-) (degS) [Bacillus velezensis strain CACC 316]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951