Detailed information NTG0418234

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: M594_RS01220
• Genome accession: NZ_CP047883
• Coordinates: 237776..238786 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090628.1
• Uniprot ID: F9HAD8
• Organism: Streptococcus mitis strain S022-V3-A4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 232776..243786

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M594_RS01195 (M594_01220)	folP	233365..234345 (+)	981	WP_023947034.1	dihydropteroate synthase	-
M594_RS01200 (M594_01225)	-	234347..235669 (+)	1323	WP_023947035.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
M594_RS01205 (M594_01230)	folE	235650..236204 (+)	555	WP_000380921.1	GTP cyclohydrolase I FolE	-
M594_RS01210 (M594_01235)	folK	236363..237175 (+)	813	WP_173875754.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
M594_RS01215 (M594_01240)	-	237221..237538 (-)	318	WP_049522427.1	DUF960 domain-containing protein	-
M594_RS01220 (M594_01245)	ccpA	237776..238786 (+)	1011	WP_001090628.1	catabolite control protein A	Regulator
M594_RS01225 (M594_01250)	-	238838..239800 (-)	963	WP_173875755.1	asparaginase	-
M594_RS01230 (M594_01255)	-	239866..241257 (+)	1392	WP_173875756.1	Cof-type HAD-IIB family hydrolase	-
M594_RS01235 (M594_01260)	-	241385..241837 (-)	453	WP_000079148.1	universal stress protein	-
M594_RS01240 (M594_01265)	-	241999..242301 (+)	303	WP_173875757.1	hypothetical protein	-
M594_RS01245 (M594_01270)	-	242458..243672 (+)	1215	WP_000666455.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37155.16 Da
• Isoelectric Point: 5.3350

>NTDB_id=418234 M594_RS01220 WP_001090628.1 237776..238786(+) (ccpA) [Streptococcus mitis strain S022-V3-A4]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQVSRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=418234 M594_RS01220 WP_001090628.1 237776..238786(+) (ccpA) [Streptococcus mitis strain S022-V3-A4]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGTGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACCCGTAAAAAAGTACTCGAGGTGATTGATCGTTTGGATTACCGTCCAAATG
CTGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATCCCCAATATCACCAATGGTTATTTCTCA
ACGCTTGCTAAAGGGATTGATGATATCGCTGAAATGTACAAGTACAATATCGTCCTTGCCAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACACTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTATCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGGACACCGGTTGTTCTTGCAGGAACTGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATTGATGCAGTAACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTCGTAAG
CGGTCCACTAGTGGATGACATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGCTATGCCTTGGCAGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAGTTGGCAGCAGGTGTTTTGAACGGCCTTGCTGATAAGGGTGTGTCAGTACC
AGAAGAATTTGAAATCATTACTAGTGATGATTCGCAAGTCTCACGCTTTACCCGTCCAAACTTGACCACTATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGTTCGACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: F9HAD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.238	100	0.952
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.222	99.405	0.887
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568