Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   H9199_RS04810 Genome accession   NZ_CP060933
Coordinates   974005..974664 (-) Length   219 a.a.
NCBI ID   WP_100729272.1    Uniprot ID   -
Organism   Escherichia coli strain EC12     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 969005..979664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9199_RS04785 (H9199_04715) parE 969096..970988 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  H9199_RS04790 (H9199_04720) ygiN 971036..971350 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  H9199_RS04795 (H9199_04725) mdaB 971381..971962 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  H9199_RS04800 (H9199_04730) ygiZ 972281..972613 (+) 333 WP_000912120.1 DUF2645 family protein -
  H9199_RS04805 (H9199_04735) qseC 972659..974008 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  H9199_RS04810 (H9199_04740) ciaR 974005..974664 (-) 660 WP_100729272.1 quorum sensing response regulator transcription factor QseB Regulator
  H9199_RS04815 (H9199_04745) ygiW 974816..975208 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  H9199_RS04820 (H9199_04750) ygiV 975261..975743 (+) 483 WP_029402277.1 GyrI-like domain-containing protein -
  H9199_RS04825 (H9199_04755) parC 976289..978547 (+) 2259 WP_001281841.1 DNA topoisomerase IV subunit A -
  H9199_RS04830 (H9199_04760) plsC 978781..979518 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24787.74 Da        Isoelectric Point: 6.6543

>NTDB_id=418006 H9199_RS04810 WP_100729272.1 974005..974664(-) (ciaR) [Escherichia coli strain EC12]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLVSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=418006 H9199_RS04810 WP_100729272.1 974005..974664(-) (ciaR) [Escherichia coli strain EC12]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTTATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGTTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.445

100

0.388
  ciaR Streptococcus pneumoniae D39

37.445

100

0.388
  ciaR Streptococcus pneumoniae R6

37.445

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

37.445

100

0.388
  ciaR Streptococcus mutans UA159

35.426

100

0.361