Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H9201_RS09505 Genome accession   NZ_CP060924
Coordinates   1986881..1987537 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC14     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1981881..1992537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9201_RS09475 (H9201_09405) dcyD 1982760..1983746 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  H9201_RS09480 (H9201_09410) tcyL 1983761..1984429 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H9201_RS09485 (H9201_09415) tcyN 1984426..1985178 (+) 753 WP_001272990.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H9201_RS09490 (H9201_09420) sdiA 1985408..1986130 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  H9201_RS09495 (H9201_09425) yecF 1986198..1986422 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H9201_RS09500 (H9201_09430) yecU 1986409..1986585 (-) 177 WP_001302050.1 protein YecU -
  H9201_RS25280 - 1986623..1986739 (-) 117 WP_001302039.1 hypothetical protein -
  H9201_RS09505 (H9201_09435) letA 1986881..1987537 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H9201_RS09510 (H9201_09440) uvrC 1987534..1989366 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  H9201_RS09515 (H9201_09445) pgsA 1989423..1989971 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H9201_RS09535 (H9201_09465) yecA 1990621..1991286 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=417859 H9201_RS09505 WP_000611328.1 1986881..1987537(+) (letA) [Escherichia coli strain EC14]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=417859 H9201_RS09505 WP_000611328.1 1986881..1987537(+) (letA) [Escherichia coli strain EC14]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482