Detailed information NTG0416533

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7786_RS02545
• Genome accession: NZ_CP060649
• Coordinates: 484730..485731 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain TSPY270
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 479730..490731

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7786_RS02520 (H7786_02555)	-	480404..481087 (-)	684	WP_030126098.1	DUF969 domain-containing protein	-
H7786_RS02525 (H7786_02560)	-	481298..482224 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
H7786_RS02530 (H7786_02565)	-	482369..482746 (-)	378	WP_002985686.1	VOC family protein	-
H7786_RS02535 (H7786_02570)	-	482748..483422 (-)	675	WP_023612169.1	NAD(P)H-dependent oxidoreductase	-
H7786_RS02540 (H7786_02575)	-	483471..484556 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
H7786_RS02545 (H7786_02580)	ccpA	484730..485731 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7786_RS02550 (H7786_02585)	-	485862..486860 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
H7786_RS02555 (H7786_02590)	-	486862..488196 (+)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
H7786_RS02560 (H7786_02595)	thrS	488618..490561 (+)	1944	WP_030126096.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=416533 H7786_RS02545 WP_002985680.1 484730..485731(+) (ccpA) [Streptococcus pyogenes strain TSPY270]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=416533 H7786_RS02545 WP_002985680.1 484730..485731(+) (ccpA) [Streptococcus pyogenes strain TSPY270]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559