Detailed information NTG0415291

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: HUG14_RS00575
• Genome accession: NZ_CP060580
• Coordinates: 122962..124329 (-)
• Length: 455 a.a.
• NCBI ID: WP_017864854.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain K_LL005
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 117962..129329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUG14_RS00560 (HUG14_00560)	-	119134..120567 (-)	1434	WP_187398443.1	6-phospho-beta-glucosidase	-
HUG14_RS00565 (HUG14_00565)	yidD	120689..120955 (-)	267	WP_012898265.1	membrane protein insertion efficiency factor YidD	-
HUG14_RS00570 (HUG14_00570)	-	121072..122814 (-)	1743	WP_010906088.1	1-deoxy-D-xylulose-5-phosphate synthase	-
HUG14_RS00575 (HUG14_00575)	ciaH	122962..124329 (-)	1368	WP_017864854.1	cell wall metabolism sensor histidine kinase WalK	Regulator
HUG14_RS00580 (HUG14_00580)	ciaR	124423..125091 (-)	669	WP_021722129.1	response regulator transcription factor	Regulator
HUG14_RS00585 (HUG14_00585)	-	125269..126243 (-)	975	WP_003130365.1	LacI family DNA-binding transcriptional regulator	-
HUG14_RS00590 (HUG14_00590)	-	126396..128651 (-)	2256	WP_187398444.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 455 a.a.
• Molecular weight: 51200.75 Da
• Isoelectric Point: 9.4771

>NTDB_id=415291 HUG14_RS00575 WP_017864854.1 122962..124329(-) (ciaH) [Lactococcus lactis strain K_LL005]
MKKIIKKIKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTSSSQD
SGFGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITNS
DGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAIL
QNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKFS
GHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKARTR
QKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1368 bp

>NTDB_id=415291 HUG14_RS00575 WP_017864854.1 122962..124329(-) (ciaH) [Lactococcus lactis strain K_LL005]
TTGAAGAAAATAATTAAAAAAATTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAGTAGTTCACAAGAC
AGTGGCTTTGGACCTAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCGTCAACGGGCTCAAATGC
AAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTCAGA
CAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAATTCT
GATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGTCGTGCCATGTG
GGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTTTGTATCTTGCAAATTGGACATTAAGAC
CTATTCTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATCTTG
CAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTTATC
AGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGCCAG
AGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTTTCA
GGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAATGC
TCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCGCCG
ATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACGCGT
CAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGAAGA
TAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCCAAA
AGTTGTAA

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (222-288)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (332-441)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.372	94.505	0.457
ciaH	Streptococcus pneumoniae Rx1	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae D39	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae R6	44.444	98.901	0.44
ciaH	Streptococcus pneumoniae TIGR4	44.444	98.901	0.44