Detailed information NTG0414904

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GNE05_RS18085
• Genome accession: NZ_CP047644
• Coordinates: 3645252..3646415 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. AM1(2019)
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3640252..3651415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNE05_RS18055 (GNE05_18055)	-	3640517..3640936 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
GNE05_RS18060 (GNE05_18060)	comFC	3641010..3641699 (-)	690	WP_201741798.1	phosphoribosyltransferase family protein	Machinery gene
GNE05_RS18065 (GNE05_18065)	-	3641705..3641989 (-)	285	WP_003151389.1	competence protein ComFB	-
GNE05_RS18070 (GNE05_18070)	comFA	3642047..3643432 (-)	1386	WP_160183055.1	DEAD/DEAH box helicase	Machinery gene
GNE05_RS18075 (GNE05_18075)	-	3643540..3644388 (-)	849	WP_072177036.1	DegV family protein	-
GNE05_RS18080 (GNE05_18080)	degU	3644486..3645175 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GNE05_RS18085 (GNE05_18085)	degS	3645252..3646415 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GNE05_RS18090 (GNE05_18090)	-	3646638..3647285 (+)	648	WP_007614107.1	YigZ family protein	-
GNE05_RS18095 (GNE05_18095)	-	3647290..3648477 (+)	1188	WP_160183056.1	LCP family protein	-
GNE05_RS18100 (GNE05_18100)	-	3648576..3649652 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
GNE05_RS18105 (GNE05_18105)	-	3649785..3650981 (-)	1197	WP_160183057.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=414904 GNE05_RS18085 WP_007407484.1 3645252..3646415(-) (degS) [Bacillus sp. AM1(2019)]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=414904 GNE05_RS18085 WP_007407484.1 3645252..3646415(-) (degS) [Bacillus sp. AM1(2019)]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAATTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951