Detailed information NTG0414795

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: H7969_RS10975
• Genome accession: NZ_CP060280
• Coordinates: 2172266..2172850 (-)
• Length: 194 a.a.
• NCBI ID: WP_002223336.1
• Uniprot ID: Q9K1A2
• Organism: Neisseria meningitidis strain LNP24198
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2167266..2177850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7969_RS10940 (H7969_10940)	-	2167543..2167842 (+)	300	WP_002215645.1	DUF2818 family protein	-
H7969_RS10945 (H7969_10945)	-	2167951..2168847 (-)	897	WP_002224264.1	polyprenyl synthetase family protein	-
H7969_RS10950 (H7969_10950)	-	2168831..2169055 (-)	225	WP_002228918.1	exodeoxyribonuclease VII small subunit	-
H7969_RS10960 (H7969_10960)	rsgA	2169319..2170242 (-)	924	WP_002224268.1	ribosome small subunit-dependent GTPase A	-
H7969_RS10965 (H7969_10965)	-	2170247..2172103 (-)	1857	WP_002224270.1	ABC transporter ATP-binding protein	-
H7969_RS10970 (H7969_10970)	-	2172129..2172266 (-)	138	WP_002231623.1	hypothetical protein	-
H7969_RS10975 (H7969_10975)	ruvA	2172266..2172850 (-)	585	WP_002223336.1	Holliday junction branch migration protein RuvA	Machinery gene
H7969_RS10980 (H7969_10980)	-	2172932..2173258 (-)	327	WP_002255647.1	PepSY domain-containing protein	-
H7969_RS10985 (H7969_10985)	-	2173312..2174031 (-)	720	WP_002221595.1	septal ring lytic transglycosylase RlpA family protein	-
H7969_RS10990 (H7969_10990)	-	2174028..2174150 (-)	123	WP_009346050.1	hypothetical protein	-
H7969_RS10995 (H7969_10995)	trmL	2174161..2174625 (-)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
H7969_RS11000 (H7969_11000)	-	2174690..2175415 (-)	726	WP_002221594.1	ComF family protein	-
H7969_RS11005 (H7969_11005)	bioH	2175414..2176157 (+)	744	WP_002221593.1	pimeloyl-ACP methyl ester esterase BioH	-
H7969_RS11010 (H7969_11010)	-	2176159..2176947 (+)	789	WP_002221592.1	hypothetical protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20687.90 Da
• Isoelectric Point: 5.3813

>NTDB_id=414795 H7969_RS10975 WP_002223336.1 2172266..2172850(-) (ruvA) [Neisseria meningitidis strain LNP24198]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLA
LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=414795 H7969_RS10975 WP_002223336.1 2172266..2172850(-) (ruvA) [Neisseria meningitidis strain LNP24198]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCAGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCCGAAGAAGATGT
CAAACGCCTGTCTTCCGCGCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAGCGAACGCGAAGCAAAAGCGGCGGTCAAAGGCGTTCCGGAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• RuvA N terminal domain (RuvA_N) (1-62)

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q9K1A2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	37.5	100	0.387
ruvA	Streptococcus pneumoniae D39	37.5	100	0.387
ruvA	Streptococcus pneumoniae TIGR4	37	100	0.381
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.437	100	0.376