Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H4P47_RS09580 Genome accession   NZ_CP060075
Coordinates   1999598..2000254 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain G3/10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994598..2005254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4P47_RS09550 (H4P47_09550) dcyD 1995477..1996463 (+) 987 WP_001128227.1 D-cysteine desulfhydrase -
  H4P47_RS09555 (H4P47_09555) tcyL 1996478..1997146 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  H4P47_RS09560 (H4P47_09560) tcyN 1997143..1997895 (+) 753 WP_047400018.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H4P47_RS09565 (H4P47_09565) sdiA 1998125..1998847 (+) 723 WP_016247298.1 transcriptional regulator SdiA -
  H4P47_RS09570 (H4P47_09570) yecF 1998915..1999139 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H4P47_RS09575 (H4P47_09575) yecU 1999126..1999302 (-) 177 WP_000590344.1 protein YecU -
  H4P47_RS25540 - 1999340..1999456 (-) 117 WP_001302039.1 hypothetical protein -
  H4P47_RS09580 (H4P47_09580) letA 1999598..2000254 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H4P47_RS09585 (H4P47_09585) uvrC 2000251..2002083 (+) 1833 WP_047400021.1 excinuclease ABC subunit UvrC Machinery gene
  H4P47_RS09590 (H4P47_09590) pgsA 2002140..2002688 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H4P47_RS09610 (H4P47_09610) yecA 2003338..2004003 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=413140 H4P47_RS09580 WP_000611328.1 1999598..2000254(+) (letA) [Escherichia coli strain G3/10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=413140 H4P47_RS09580 WP_000611328.1 1999598..2000254(+) (letA) [Escherichia coli strain G3/10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment