Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GQF93_RS11230 Genome accession   NZ_CP059835
Coordinates   2303179..2303838 (+) Length   219 a.a.
NCBI ID   WP_212487630.1    Uniprot ID   -
Organism   Escherichia coli strain tcmA_3     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2298179..2308838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQF93_RS11210 (GQF93_11210) plsC 2298325..2299062 (-) 738 WP_000965703.1 1-acylglycerol-3-phosphate O-acyltransferase -
  GQF93_RS11215 (GQF93_11215) parC 2299296..2301554 (-) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  GQF93_RS11220 (GQF93_11220) ygiV 2302100..2302582 (-) 483 WP_000183494.1 GyrI-like domain-containing protein -
  GQF93_RS11225 (GQF93_11225) ygiW 2302635..2303027 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  GQF93_RS11230 (GQF93_11230) ciaR 2303179..2303838 (+) 660 WP_212487630.1 quorum sensing response regulator transcription factor QseB Regulator
  GQF93_RS11235 (GQF93_11235) qseC 2303835..2305184 (+) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  GQF93_RS11240 (GQF93_11240) ygiZ 2305230..2305562 (-) 333 WP_000912120.1 DUF2645 family protein -
  GQF93_RS11245 (GQF93_11245) mdaB 2305881..2306462 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  GQF93_RS11250 (GQF93_11250) ygiN 2306493..2306807 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  GQF93_RS11255 (GQF93_11255) parE 2306855..2308747 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=411210 GQF93_RS11230 WP_212487630.1 2303179..2303838(+) (ciaR) [Escherichia coli strain tcmA_3]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDLLREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=411210 GQF93_RS11230 WP_212487630.1 2303179..2303838(+) (ciaR) [Escherichia coli strain tcmA_3]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATCTTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365