Detailed information NTG0410767

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: GQ677_RS10110
• Genome accession: NZ_CP047120
• Coordinates: 1984789..1985223 (-)
• Length: 144 a.a.
• NCBI ID: WP_023612536.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1085
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1979789..1990223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQ677_RS10085 (GQ677_10085)	proC	1980825..1981595 (+)	771	WP_136274084.1	pyrroline-5-carboxylate reductase	-
GQ677_RS10090 (GQ677_10090)	-	1981678..1981986 (-)	309	WP_010921804.1	hypothetical protein	-
GQ677_RS10095 (GQ677_10095)	-	1982173..1983369 (-)	1197	WP_023612537.1	acetate kinase	-
GQ677_RS10100 (GQ677_10100)	comYH	1983428..1984381 (-)	954	WP_136274080.1	class I SAM-dependent methyltransferase	Machinery gene
GQ677_RS10105 (GQ677_10105)	comGG	1984479..1984805 (-)	327	WP_136274078.1	competence type IV pilus minor pilin ComGG	-
GQ677_RS10110 (GQ677_10110)	comYF	1984789..1985223 (-)	435	WP_023612536.1	competence type IV pilus minor pilin ComGF	Machinery gene
GQ677_RS10115 (GQ677_10115)	comGE	1985216..1985500 (-)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
GQ677_RS10120 (GQ677_10120)	comGD	1985457..1985885 (-)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
GQ677_RS10125 (GQ677_10125)	comYC	1985860..1986186 (-)	327	WP_032465607.1	competence type IV pilus major pilin ComGC	Machinery gene
GQ677_RS10130 (GQ677_10130)	comYB	1986188..1987222 (-)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
GQ677_RS10135 (GQ677_10135)	comYA	1987158..1988096 (-)	939	WP_002986557.1	competence type IV pilus ATPase ComGA	Machinery gene
GQ677_RS10140 (GQ677_10140)	-	1988189..1988554 (-)	366	WP_002986560.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16688.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=410767 GQ677_RS10110 WP_023612536.1 1984789..1985223(-) (comYF) [Streptococcus pyogenes strain 1085]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=410767 GQ677_RS10110 WP_023612536.1 1984789..1985223(-) (comYF) [Streptococcus pyogenes strain 1085]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	50.36	96.528	0.486
comYF	Streptococcus mutans UA159	49.64	96.528	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	93.056	0.403
comGF/cglF	Streptococcus pneumoniae Rx1	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae D39	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae R6	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae TIGR4	42.105	92.361	0.389
comGF/cglF	Streptococcus mitis SK321	41.353	92.361	0.382