Detailed information NTG0410752

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GQ677_RS08545
• Genome accession: NZ_CP047120
• Coordinates: 1672211..1673212 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 1085
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1667211..1678212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQ677_RS08530 (GQ677_08530)	thrS	1667381..1669324 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
GQ677_RS08535 (GQ677_08535)	-	1669746..1671080 (-)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
GQ677_RS08540 (GQ677_08540)	-	1671082..1672080 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
GQ677_RS08545 (GQ677_08545)	ccpA	1672211..1673212 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
GQ677_RS08550 (GQ677_08550)	-	1673386..1674471 (+)	1086	WP_030126780.1	aminopeptidase P family protein	-
GQ677_RS08555 (GQ677_08555)	-	1674520..1675185 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
GQ677_RS08560 (GQ677_08560)	-	1675196..1675573 (+)	378	WP_002985686.1	VOC family protein	-
GQ677_RS08565 (GQ677_08565)	-	1675718..1676644 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
GQ677_RS08570 (GQ677_08570)	-	1676855..1677538 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=410752 GQ677_RS08545 WP_002985680.1 1672211..1673212(-) (ccpA) [Streptococcus pyogenes strain 1085]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=410752 GQ677_RS08545 WP_002985680.1 1672211..1673212(-) (ccpA) [Streptococcus pyogenes strain 1085]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559