Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SGPB_RS02255 Genome accession   NC_015600
Coordinates   423083..424384 (+) Length   433 a.a.
NCBI ID   WP_003063550.1    Uniprot ID   E0PC02
Organism   Streptococcus pasteurianus ATCC 43144     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 418083..429384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS02230 (SGPB_0398) - 418737..419381 (+) 645 WP_013851527.1 response regulator transcription factor -
  SGPB_RS02235 (SGPB_0399) - 419499..420899 (+) 1401 WP_013851528.1 Cof-type HAD-IIB family hydrolase -
  SGPB_RS02240 (SGPB_0400) - 420899..421255 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  SGPB_RS02245 (SGPB_0401) cysK 421368..422297 (-) 930 WP_013851529.1 cysteine synthase A -
  SGPB_RS02250 (SGPB_0402) - 422401..423027 (-) 627 WP_013851530.1 YigZ family protein -
  SGPB_RS02255 (SGPB_0403) comFA/cflA 423083..424384 (+) 1302 WP_003063550.1 DEAD/DEAH box helicase Machinery gene
  SGPB_RS02260 (SGPB_0404) comFC/cflB 424381..425043 (+) 663 WP_013851531.1 ComF family protein Machinery gene
  SGPB_RS02265 (SGPB_0405) hpf 425119..425667 (+) 549 WP_003063557.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SGPB_RS11250 - 425802..426497 (+) 696 Protein_407 transposase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49398.54 Da        Isoelectric Point: 10.0600

>NTDB_id=41066 SGPB_RS02255 WP_003063550.1 423083..424384(+) (comFA/cflA) [Streptococcus pasteurianus ATCC 43144]
MDKLNNYYGRLFTQAQLSDALKKQAKQLPAMTKLNHHYICNRCGSQVSLQNKLQTNVFYCRNCLVFGRNTSNGHLYYFPQ
RRFSKKDSLIWKGKLTPYQDDVSKGMLEGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFSCLITLLHGDSEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDRAIKPNRTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGVLSNMQKKKIPQKLINLIKKQRQTHYPLLIFFPNIEQGEAFTQI
LQTYFSEEQIAFVSSKTENRLDIVEKFRRQELSILVTTTILERGVTFPCVDVFVLLSNHRLYTKSTLVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAIAEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=41066 SGPB_RS02255 WP_003063550.1 423083..424384(+) (comFA/cflA) [Streptococcus pasteurianus ATCC 43144]
ATGGATAAACTGAATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAGCAGGCTAAACA
GTTGCCGGCAATGACAAAATTAAATCATCATTATATCTGTAATCGTTGTGGTAGTCAAGTGTCTTTACAAAATAAACTTC
AAACAAACGTTTTTTATTGTCGAAATTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AGACGTTTTTCTAAAAAAGATTCTCTTATTTGGAAAGGAAAATTGACCCCTTACCAAGATGATGTTTCAAAAGGGATGTT
AGAAGGCATTGATGCTAAGAAAGACCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGCCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAGCTTTATAAACGC
TTGTCACGTGATTTTTCGTGTCTGATTACATTGCTTCATGGAGATTCTGAGCCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAGAGCTATCAAACCTAATAGAACCAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACTAAATTGCACCTTGCTCGACGATTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGCGTTTTATCCAATATGCAAAAGAAGAAAATTCCCCAGAAATTAATAAATCTTA
TAAAAAAACAACGTCAAACCCACTATCCTTTGCTAATTTTCTTCCCAAATATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAGACCTATTTTTCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGACATTGTAGAAAAATT
TAGGAGACAAGAACTTTCTATTTTGGTGACAACAACCATTTTAGAACGTGGTGTAACTTTCCCTTGTGTAGATGTCTTTG
TATTGCTTTCCAATCATAGATTATACACCAAAAGCACGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAACTGTTATTCTTGCATGACGGTAGTACCAAAGAAATGAGGAAAGCTATTGCTGAAATTAAAGCGATGAA
TAAAAAAGGAGGATTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PC02

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis SK321

58.548

98.614

0.577
  comFA Lactococcus lactis subsp. cremoris KW2

50

94.226

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

99.538

0.376

Multiple sequence alignment