Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H1A19_RS06520 Genome accession   NZ_CP059383
Coordinates   1247271..1248584 (+) Length   437 a.a.
NCBI ID   WP_000042580.1    Uniprot ID   Q8DZW2
Organism   Streptococcus agalactiae strain BJ01     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1242271..1253584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1A19_RS06500 (H1A19_06500) pstB 1242305..1243063 (+) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -
  H1A19_RS06505 (H1A19_06505) phoU 1243097..1243750 (+) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  H1A19_RS06510 (H1A19_06510) - 1243896..1246445 (+) 2550 WP_000859382.1 M1 family metallopeptidase -
  H1A19_RS06515 (H1A19_06515) ciaR 1246607..1247287 (+) 681 WP_000590620.1 response regulator transcription factor Regulator
  H1A19_RS06520 (H1A19_06520) ciaH 1247271..1248584 (+) 1314 WP_000042580.1 cell wall metabolism sensor histidine kinase WalK Regulator
  H1A19_RS06525 (H1A19_06525) - 1248673..1249005 (+) 333 WP_000402075.1 putative DNA-binding protein -
  H1A19_RS06530 (H1A19_06530) ffh 1249023..1250588 (+) 1566 WP_000863589.1 signal recognition particle protein -
  H1A19_RS06535 (H1A19_06535) - 1250655..1251341 (+) 687 WP_000280308.1 SatD family protein -
  H1A19_RS06540 (H1A19_06540) - 1251331..1252104 (+) 774 WP_000622398.1 DUF3307 domain-containing protein -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49708.14 Da        Isoelectric Point: 9.4961

>NTDB_id=410213 H1A19_RS06520 WP_000042580.1 1247271..1248584(+) (ciaH) [Streptococcus agalactiae strain BJ01]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLITQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=410213 H1A19_RS06520 WP_000042580.1 1247271..1248584(+) (ciaH) [Streptococcus agalactiae strain BJ01]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCACCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae D39

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae R6

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.781

96.339

0.499

Multiple sequence alignment