Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   H0155_RS03365 Genome accession   NZ_CP059283
Coordinates   693632..694291 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain SY3626_hybrid     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 688632..699291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0155_RS03340 (H0155_03340) parE 688723..690615 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  H0155_RS03345 (H0155_03345) ygiN 690663..690977 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  H0155_RS03350 (H0155_03350) mdaB 691008..691589 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  H0155_RS03355 (H0155_03355) ygiZ 691908..692240 (+) 333 WP_000917684.1 DUF2645 family protein -
  H0155_RS03360 (H0155_03360) qseC 692286..693635 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  H0155_RS03365 (H0155_03365) ciaR 693632..694291 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  H0155_RS03370 (H0155_03370) ygiW 694443..694835 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  H0155_RS03375 (H0155_03375) ygiV 694888..695370 (+) 483 WP_001652148.1 GyrI-like domain-containing protein -
  H0155_RS03380 (H0155_03380) mqsR 695575..695871 (+) 297 WP_176580470.1 type II toxin-antitoxin system toxin MqsR -
  H0155_RS03385 (H0155_03385) mqsA 695873..696268 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  H0155_RS03390 (H0155_03390) ygiS 696401..698008 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=409449 H0155_RS03365 WP_001221493.1 693632..694291(-) (ciaR) [Escherichia coli strain SY3626_hybrid]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=409449 H0155_RS03365 WP_001221493.1 693632..694291(-) (ciaR) [Escherichia coli strain SY3626_hybrid]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment