Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GPZ88_RS01755 Genome accession   NZ_CP046919
Coordinates   329992..331344 (-) Length   450 a.a.
NCBI ID   WP_166043168.1    Uniprot ID   A0A6G8HYK1
Organism   Streptococcus ruminicola strain CNU_G2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 324992..336344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS01745 (GPZ88_01725) rnc 328274..328960 (-) 687 WP_020917219.1 ribonuclease III -
  GPZ88_RS01750 (GPZ88_01730) vicX 329182..329991 (-) 810 WP_074602529.1 MBL fold metallo-hydrolase Regulator
  GPZ88_RS01755 (GPZ88_01735) vicK 329992..331344 (-) 1353 WP_166043168.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPZ88_RS01760 (GPZ88_01740) vicR 331337..332047 (-) 711 WP_039696509.1 response regulator YycF Regulator
  GPZ88_RS01765 (GPZ88_01745) - 332359..333123 (+) 765 WP_166043170.1 amino acid ABC transporter ATP-binding protein -
  GPZ88_RS01770 (GPZ88_01750) - 333134..333946 (+) 813 WP_166043172.1 transporter substrate-binding domain-containing protein -
  GPZ88_RS01775 (GPZ88_01755) - 333962..334669 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  GPZ88_RS01780 (GPZ88_01760) - 334682..335329 (+) 648 WP_006532766.1 amino acid ABC transporter permease -
  GPZ88_RS01785 (GPZ88_01765) - 335367..335975 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.32 Da        Isoelectric Point: 4.7300

>NTDB_id=409395 GPZ88_RS01755 WP_166043168.1 329992..331344(-) (vicK) [Streptococcus ruminicola strain CNU_G2]
MNNIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYTYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=409395 GPZ88_RS01755 WP_166043168.1 329992..331344(-) (vicK) [Streptococcus ruminicola strain CNU_G2]
ATGAATAATATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTATATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGCTTGGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTACATGACTGATGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACAGCTCAGCAGCAACTTAATCTGGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGACGATAGCGATTATACCTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGCCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTAAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTGATTGCTGTTTTACATGATACAACGGAACAGGAAAAAGAAGACCGTGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAATTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAGGCACTGGATGAAGGGGCTCTGAAA
GAAGATATTGCACCAAGTTTCATTAAAGTTTCTTTGGATGAAACCAACCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACGAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAGAGCCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCGATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACCCAGGTCTTGGATAATATCCTAAATAATGCCATTAAGTATTCACCAGA
CGGTGGTAAAATCACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HYK1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622

Multiple sequence alignment