Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   GPX94_RS12380 Genome accession   NZ_CP046848
Coordinates   2639632..2641761 (-) Length   709 a.a.
NCBI ID   WP_229601138.1    Uniprot ID   -
Organism   Vibrio cincinnatiensis strain F8054     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2622643..2647189 2639632..2641761 within 0


Gene organization within MGE regions


Location: 2622643..2647189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPX94_RS12315 - 2622643..2623413 (-) 771 WP_078926292.1 ATP-binding cassette domain-containing protein -
  GPX94_RS12320 - 2624019..2625563 (+) 1545 WP_078926291.1 DUF3360 family protein -
  GPX94_RS12325 pflB 2625901..2628177 (+) 2277 WP_154115769.1 formate C-acetyltransferase -
  GPX94_RS12330 pflA 2628375..2629115 (+) 741 WP_078926289.1 pyruvate formate lyase 1-activating protein -
  GPX94_RS12335 - 2629358..2629858 (+) 501 WP_078926288.1 YfbU family protein -
  GPX94_RS12340 - 2629916..2630671 (-) 756 WP_154115770.1 MipA/OmpV family protein -
  GPX94_RS12345 - 2630968..2632902 (+) 1935 WP_078926286.1 PrkA family serine protein kinase -
  GPX94_RS12350 - 2633013..2634284 (+) 1272 WP_078926285.1 YeaH/YhbH family protein -
  GPX94_RS12355 - 2634296..2635834 (+) 1539 WP_158147646.1 SpoVR family protein -
  GPX94_RS12360 kdsB 2635932..2636681 (-) 750 WP_154115772.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  GPX94_RS12365 - 2636681..2636860 (-) 180 WP_078926282.1 Trm112 family protein -
  GPX94_RS12370 lpxK 2636841..2637848 (-) 1008 WP_078926281.1 tetraacyldisaccharide 4'-kinase -
  GPX94_RS12375 msbA 2637852..2639599 (-) 1748 Protein_2343 lipid A ABC transporter ATP-binding protein/permease MsbA -
  GPX94_RS12380 comEC 2639632..2641761 (-) 2130 WP_229601138.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GPX94_RS12385 - 2641884..2642399 (+) 516 WP_154115775.1 DUF2062 domain-containing protein -
  GPX94_RS12390 - 2642649..2643269 (+) 621 WP_154115929.1 NAD(P)H-dependent oxidoreductase -
  GPX94_RS12395 - 2643266..2645188 (+) 1923 WP_154115776.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
  GPX94_RS12400 lolE 2645265..2646503 (-) 1239 WP_154115777.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  GPX94_RS12405 lolD 2646503..2647189 (-) 687 WP_078926275.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 80117.63 Da        Isoelectric Point: 8.8044

>NTDB_id=408885 GPX94_RS12380 WP_229601138.1 2639632..2641761(-) (comEC) [Vibrio cincinnatiensis strain F8054]
MSMMLFMNRCRGCIGVALALVVIITQGNLVRAQSNIILQFEGDITIKGEVNSFFNATSHGFVGSAVIRSINHQPLPFFLT
PKIHLTTPIALQLGDQFEFIAQVKPIYGRLNEVGFDQESFYFSQRWVARANVKKNSTYQIIPNSHLRSKLYSHIKQLTEL
SPVQGMILALTFGERSLITAEQWLGLRNSGLIHLTAISGLHIGMAFGVGYVFGLLLIRILTGRLWLPFVLGGGLALAYAW
LAGFTLPTQRALIMCWLNIVLLLLNVRVTAIQRILLTLSAVALWDPFTALSASFWLSFLAVSLVIYQISTINPQFVWWKK
LLLGQFRLSILMVPMSAYFFAGVSLSSVLYNILFIPWFSFVVIPLLFMALICYLLFQYESSWWWEWLESALWPFNVSLGL
SSPSWIDVSLSSQYFLLMILTLWFLRPMLSKSAGIAITMIVAMGWVSFPDKQGWRVDVLDVGHGLAVLIERNGAFVLYDT
GSGWEGGSYAQSLIAPLLIHRGYSHLDGVIISHFDNDHSGGLYDIQRLLSPIWIRASQHKPSIQPCKQGEQWQWQGLTFT
ALWPPQLVSRAENPHSCVVRIEDPEYGHSLLLTGDVTAVGEWLLSREAEILESDVLLVPHHGSQTSSTLAFIKTVNPQIA
LASLAKGHRWRLPHPDVLSRYQDLGINWLDTGDMGQISLLYRKEDRQLQTLRQRGIRPWYRQMLRNEVE

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=408885 GPX94_RS12380 WP_229601138.1 2639632..2641761(-) (comEC) [Vibrio cincinnatiensis strain F8054]
ATGAGTATGATGTTATTCATGAACCGTTGCAGGGGATGCATCGGGGTCGCTCTGGCTTTGGTGGTAATAATAACACAAGG
AAACTTGGTGAGAGCACAGTCCAATATAATCTTACAATTTGAGGGCGATATTACCATAAAAGGAGAGGTTAACAGCTTTT
TTAACGCAACTTCACACGGTTTTGTTGGTTCGGCGGTTATTCGTTCAATTAATCATCAGCCTTTACCCTTTTTTCTAACA
CCTAAGATACATTTAACGACGCCTATCGCATTACAGCTGGGGGATCAATTTGAGTTTATTGCGCAAGTGAAACCCATTTA
TGGACGGTTAAATGAAGTTGGGTTTGATCAGGAGTCTTTTTACTTTAGCCAGCGTTGGGTTGCCCGTGCAAATGTTAAAA
AAAATTCAACCTATCAAATTATACCCAATAGCCATTTACGTTCGAAGCTCTATTCCCATATTAAACAGCTCACAGAGTTG
AGCCCAGTACAAGGTATGATACTTGCCCTGACTTTTGGTGAGCGCAGTTTGATTACCGCTGAGCAGTGGTTAGGGCTGCG
TAATAGCGGCCTGATTCATTTAACGGCAATCTCGGGGTTACATATTGGGATGGCGTTTGGGGTGGGGTATGTGTTTGGGT
TGTTATTAATTCGAATACTTACGGGGCGGCTGTGGCTGCCTTTTGTACTCGGAGGGGGGCTGGCATTGGCTTATGCTTGG
CTTGCTGGGTTTACGTTGCCCACCCAACGTGCATTAATTATGTGTTGGTTAAACATAGTGCTGCTATTACTCAATGTTCG
AGTCACCGCAATACAGCGAATATTACTGACCTTGTCTGCCGTGGCACTGTGGGATCCATTCACGGCTCTTTCGGCGAGTT
TTTGGCTATCTTTTCTCGCAGTGAGTTTGGTGATTTATCAAATATCGACCATCAACCCACAATTCGTTTGGTGGAAAAAA
CTCCTTTTGGGGCAGTTTCGTTTGTCAATATTAATGGTTCCAATGAGCGCTTATTTCTTTGCTGGCGTTAGCTTATCTTC
GGTTCTCTATAACATATTATTCATTCCGTGGTTCAGTTTTGTGGTGATTCCACTGCTATTTATGGCCTTAATTTGCTACC
TATTATTTCAGTATGAATCCTCTTGGTGGTGGGAATGGCTAGAGAGCGCTTTATGGCCGTTCAATGTGTCATTGGGTTTA
TCGTCTCCGAGTTGGATTGATGTTAGTTTATCCTCTCAATATTTTTTGCTGATGATACTGACGCTATGGTTTCTTAGGCC
AATGTTATCGAAGAGCGCTGGGATTGCGATAACGATGATTGTGGCAATGGGATGGGTCAGCTTTCCTGATAAACAAGGCT
GGCGAGTAGATGTGTTGGATGTTGGACATGGTTTGGCTGTACTCATTGAACGAAACGGTGCTTTTGTTTTGTATGACACA
GGCAGTGGCTGGGAAGGTGGTAGCTATGCTCAATCATTGATAGCCCCTCTGCTTATTCATCGAGGATATAGCCATCTTGA
TGGTGTGATCATTAGCCACTTTGATAATGATCATTCAGGGGGCTTGTATGACATTCAGCGGTTACTTTCTCCGATTTGGA
TTCGCGCTAGTCAGCATAAGCCTAGTATTCAACCTTGCAAACAAGGTGAGCAGTGGCAGTGGCAAGGGTTAACTTTTACT
GCACTCTGGCCTCCGCAGCTCGTTTCTCGGGCAGAAAATCCGCATTCTTGTGTGGTACGTATTGAAGACCCTGAATACGG
CCATTCTTTATTGTTGACTGGCGATGTAACCGCGGTGGGCGAGTGGTTATTGAGTCGAGAGGCTGAGATATTAGAAAGTG
ATGTTCTGCTCGTGCCACATCATGGTAGTCAAACCTCATCAACCCTTGCTTTCATCAAGACAGTGAATCCACAGATTGCA
TTAGCTTCTTTAGCAAAGGGGCATCGCTGGCGTTTACCTCATCCGGATGTGTTGTCTCGTTATCAAGATTTAGGGATCAA
CTGGTTAGATACTGGGGATATGGGGCAAATTTCTTTACTCTATCGAAAAGAAGATCGCCAGTTACAGACGCTTCGTCAGA
GAGGAATTCGGCCGTGGTATAGGCAGATGCTACGTAACGAGGTAGAATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(461-641)

Competence protein (Competence)

(170-423)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

50.07

100

0.502
  comEC Vibrio campbellii strain DS40M4

42.297

100

0.426
  comEC Vibrio parahaemolyticus RIMD 2210633

41.877

100

0.422

Multiple sequence alignment