Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GPW86_RS11335 Genome accession   NZ_CP046742
Coordinates   1195813..1196445 (+) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain 3523-03     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1190813..1201445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW86_RS11310 - 1190878..1192794 (+) 1917 WP_000627674.1 ABC transporter ATP-binding protein -
  GPW86_RS11315 - 1192795..1193280 (+) 486 WP_001278734.1 TIGR02444 family protein -
  GPW86_RS11320 - 1193277..1194266 (+) 990 WP_000206394.1 hydrolase -
  GPW86_RS11325 - 1194395..1194604 (+) 210 WP_000586561.1 YheU family protein -
  GPW86_RS11330 - 1194701..1195570 (+) 870 WP_001274667.1 phosphoribulokinase -
  GPW86_RS11335 crp 1195813..1196445 (+) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  GPW86_RS11340 - 1196524..1197315 (-) 792 WP_114974524.1 DUF1338 domain-containing protein -
  GPW86_RS11345 astD 1197458..1198915 (-) 1458 WP_095471431.1 succinylglutamate-semialdehyde dehydrogenase -
  GPW86_RS11350 astA 1198925..1199944 (-) 1020 WP_002162681.1 arginine N-succinyltransferase -
  GPW86_RS11355 - 1200084..1201295 (-) 1212 WP_113597295.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=406958 GPW86_RS11335 WP_000242749.1 1195813..1196445(+) (crp) [Vibrio cholerae strain 3523-03]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=406958 GPW86_RS11335 WP_000242749.1 1195813..1196445(+) (crp) [Vibrio cholerae strain 3523-03]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment