Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GPW74_RS08285 Genome accession   NZ_CP046737
Coordinates   1847207..1847839 (+) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain 2015V-1126     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1842207..1852839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW74_RS08260 - 1842288..1844204 (+) 1917 WP_000627681.1 ABC transporter ATP-binding protein -
  GPW74_RS08265 - 1844205..1844690 (+) 486 WP_001278733.1 TIGR02444 family protein -
  GPW74_RS08270 - 1844687..1845676 (+) 990 WP_000206394.1 hydrolase -
  GPW74_RS08275 - 1845789..1845998 (+) 210 WP_001888622.1 YheU family protein -
  GPW74_RS08280 - 1846095..1846964 (+) 870 WP_001274667.1 phosphoribulokinase -
  GPW74_RS08285 crp 1847207..1847839 (+) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  GPW74_RS08290 - 1847918..1848709 (-) 792 WP_000189091.1 DUF1338 domain-containing protein -
  GPW74_RS08295 astD 1848852..1850309 (-) 1458 WP_123012519.1 succinylglutamate-semialdehyde dehydrogenase -
  GPW74_RS08300 astA 1850319..1851338 (-) 1020 WP_000962042.1 arginine N-succinyltransferase -
  GPW74_RS08305 - 1851478..1852689 (-) 1212 WP_113597295.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=406862 GPW74_RS08285 WP_000242749.1 1847207..1847839(+) (crp) [Vibrio cholerae strain 2015V-1126]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=406862 GPW74_RS08285 WP_000242749.1 1847207..1847839(+) (crp) [Vibrio cholerae strain 2015V-1126]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCGAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCCGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment