Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   GPW74_RS04740 Genome accession   NZ_CP046737
Coordinates   1097191..1099320 (-) Length   709 a.a.
NCBI ID   WP_238689178.1    Uniprot ID   -
Organism   Vibrio cholerae strain 2015V-1126     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1092191..1104320
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW74_RS04720 kdsB 1093484..1094242 (-) 759 WP_123012388.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  GPW74_RS04725 - 1094242..1094421 (-) 180 WP_000350068.1 Trm112 family protein -
  GPW74_RS04730 lpxK 1094402..1095409 (-) 1008 WP_002034410.1 tetraacyldisaccharide 4'-kinase -
  GPW74_RS04735 msbA 1095412..1097160 (-) 1749 WP_000052155.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  GPW74_RS04740 comEC 1097191..1099320 (-) 2130 WP_238689178.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GPW74_RS04745 - 1099443..1099973 (+) 531 WP_001881633.1 DUF2062 domain-containing protein -
  GPW74_RS04755 lolE 1100088..1101332 (-) 1245 WP_000493013.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  GPW74_RS04760 lolD 1101333..1102019 (-) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  GPW74_RS04765 lolC 1102012..1103220 (-) 1209 WP_162796716.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  GPW74_RS04770 - 1103396..1103971 (+) 576 WP_111673968.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 79858.12 Da        Isoelectric Point: 7.5763

>NTDB_id=406854 GPW74_RS04740 WP_238689178.1 1097191..1099320(-) (comEC) [Vibrio cholerae strain 2015V-1126]
MVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGPDIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTR
PRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYMAQSVVARAAVKPDTAYQIVQESGIRSSLFFELEQLTHT
SPYQGLILALTFGERKGIDEPEWQALRNSGLIHLVAISGLHIGIAFSVGYFLGLGMMRLHAQLLWSPFVCGALLAVLYAW
LAGFTLPTQRALIMCLLNVALVMLAFPLSALKRILLTLVAVLLWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKA
LLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVIVPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQF
ADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMMGLWWWFPSLTPLWRMDVLDVGHGLAIVIEQDEQAIVYDT
GSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDWQGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFT
VLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEWLLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLA
IASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFYPDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=406854 GPW74_RS04740 WP_238689178.1 1097191..1099320(-) (comEC) [Vibrio cholerae strain 2015V-1126]
ATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCTTCGTGGCTGCCATACTAACCATTGTGCTACAGGG
CAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCGGATATTATCATAAAAGGCCGTGTTGACAGCTTTT
TTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGAAGTGAATGGACAAACCTTAAACAAAATGACTCGC
CCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACCGCGTCGAATTTTCGGTAACTCTCAAGCCGATAGT
GGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATGGCGCAATCTGTCGTCGCACGGGCGGCCGTAAAAC
CTGACACTGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAGTTTGTTTTTTGAGCTAGAACAATTAACGCATACC
AGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAAAAGGTATTGATGAGCCAGAGTGGCAAGCCTTACG
CAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTACACATTGGTATCGCTTTTAGCGTGGGTTATTTTCTCGGGC
TCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGTGTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGG
CTGGCCGGATTTACTCTGCCCACTCAGCGCGCATTGATCATGTGCTTACTCAATGTGGCGTTGGTCATGTTGGCTTTTCC
TCTTTCCGCGCTCAAGCGGATTTTACTCACCTTAGTCGCGGTCTTGCTTTGGTCGCCATTCGCCTCACTTTCAAACAGTT
TCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGCCAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCT
CTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCACGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGC
AGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATTGTCCCAGCTTTGTTTTTGGGCCTACTACTCATGG
TGGTATGGCCCAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTGGACGTTTTTACCGCTCGATTGGGCTTTGCAGTTT
GCCGATGTAGGCTGGTGGGTGGTACCCAGCAAAGTACAAGGTGTAGTCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCG
ATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATGGGCTTATGGTGGTGGTTTCCCTCCCTCACTCCACTTT
GGCGAATGGACGTGCTGGATGTTGGACATGGCTTGGCGATTGTGATTGAGCAAGATGAGCAAGCAATTGTCTACGATACA
GGCAGCAGTTGGCCGGGAGGCAGTTATGTGCAAAGCGTGATTGAGCCTATTCTCCAACAGCGAGGGCTACGCCAAGTCGA
TGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGGCAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGA
TTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGGTGAAAGCTGGCAGTGGCAATCTCTCCATTTTACG
GTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATTCGTGTGTGATTCGTATGACTGATACTCAGTCTAA
CCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGGCTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTG
AGGTGATGATCGTGCCGCATCACGGCAGTAAAACGTCGTCCACCGCAGAGTTTATTGCCCAAGTGAATCCCAAACTTGCG
ATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGCAAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGA
GTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTTTCTATCCAGATCAGCTGGATTGGTTTACCCAGCGTAGCC
TTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(6-135)

Competence protein (Competence)

(170-426)

Metallo-beta-lactamase superfamily (Lactamase_B)

(461-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

98.872

100

0.989
  comEC Vibrio parahaemolyticus RIMD 2210633

41.292

100

0.415
  comEC Vibrio campbellii strain DS40M4

41.16

99.718

0.41

Multiple sequence alignment