Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GPW66_RS08930 Genome accession   NZ_CP046736
Coordinates   889675..890307 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain 3528-08     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 884675..895307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW66_RS08910 - 884825..886036 (+) 1212 WP_000215474.1 aspartate aminotransferase family protein -
  GPW66_RS08915 astA 886176..887195 (+) 1020 WP_071181326.1 arginine N-succinyltransferase -
  GPW66_RS08920 astD 887205..888662 (+) 1458 WP_032472757.1 succinylglutamate-semialdehyde dehydrogenase -
  GPW66_RS08925 - 888805..889596 (+) 792 WP_001888623.1 DUF1338 domain-containing protein -
  GPW66_RS08930 crp 889675..890307 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  GPW66_RS08935 - 890550..891419 (-) 870 WP_001274667.1 phosphoribulokinase -
  GPW66_RS08940 - 891516..891725 (-) 210 WP_001888622.1 YheU family protein -
  GPW66_RS08945 - 891854..892843 (-) 990 WP_001888620.1 hydrolase -
  GPW66_RS08950 - 892840..893325 (-) 486 WP_001278734.1 TIGR02444 family protein -
  GPW66_RS08955 - 893326..895242 (-) 1917 WP_032472758.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=406831 GPW66_RS08930 WP_000242749.1 889675..890307(-) (crp) [Vibrio cholerae strain 3528-08]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=406831 GPW66_RS08930 WP_000242749.1 889675..890307(-) (crp) [Vibrio cholerae strain 3528-08]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
TCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment