Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GO995_RS02530 Genome accession   NZ_CP046624
Coordinates   472380..473678 (+) Length   432 a.a.
NCBI ID   WP_157628772.1    Uniprot ID   -
Organism   Streptococcus ruminicola strain CNU_G3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 467380..478678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO995_RS02505 (GO995_02505) - 468047..468691 (+) 645 WP_006531177.1 response regulator transcription factor -
  GO995_RS02510 (GO995_02510) - 468816..470216 (+) 1401 WP_157628770.1 Cof-type HAD-IIB family hydrolase -
  GO995_RS02515 (GO995_02515) - 470216..470572 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  GO995_RS02520 (GO995_02520) cysK 470670..471599 (-) 930 WP_157628771.1 cysteine synthase A -
  GO995_RS02525 (GO995_02525) - 471699..472325 (-) 627 WP_074626742.1 YigZ family protein -
  GO995_RS02530 (GO995_02530) comFA/cflA 472380..473678 (+) 1299 WP_157628772.1 DEAD/DEAH box helicase Machinery gene
  GO995_RS02535 (GO995_02535) - 473678..474340 (+) 663 WP_157628773.1 ComF family protein -
  GO995_RS02540 (GO995_02540) hpf 474417..474965 (+) 549 WP_039695883.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49080.41 Da        Isoelectric Point: 9.8826

>NTDB_id=406158 GO995_RS02530 WP_157628772.1 472380..473678(+) (comFA/cflA) [Streptococcus ruminicola strain CNU_G3]
MTELNDYYGRIFTESQLTDDLKKEAKVLPSVKKEKGQMICNRCGSVMEANQMLQTGRIYCRECLVFGRNTSDSNLYYFPQ
KPFTKTQSLKWQGKLTPYQDEVSKGMLKGITEKQDLLIHAVTGAGKTEMIYQSLAKVIDNGGSVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSEPYKRSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYHAVNQSLKDDGVKLFLTATST
DELDKKVKKGELTKLHLARRFHANPLVVPKMVWLSKVLIAMKKKKLPPKLISLLKKQRQSQFPLLIFFPNIEQGREFTSI
LQTTFPDERIGFVSSKTENRLELVEEFRQGKLTILVTTTILERGVTFPCVDVFVLLANHKLYSKSALVQISGRVGRAAER
PTGELLFLHDGVTKAMKKAISEIKEMNHKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=406158 GO995_RS02530 WP_157628772.1 472380..473678(+) (comFA/cflA) [Streptococcus ruminicola strain CNU_G3]
ATGACAGAGTTAAATGATTACTATGGAAGAATTTTTACAGAAAGTCAGTTAACAGATGACTTGAAAAAGGAAGCAAAAGT
CCTTCCTTCGGTTAAAAAGGAAAAAGGGCAAATGATTTGCAATCGCTGTGGAAGTGTAATGGAAGCAAATCAAATGTTGC
AAACTGGTCGCATTTATTGTAGAGAGTGTTTAGTTTTTGGGCGAAATACTAGTGATTCTAATCTTTATTATTTCCCTCAG
AAGCCTTTTACAAAGACTCAGTCTTTAAAGTGGCAAGGAAAACTAACTCCTTATCAAGATGAAGTTTCTAAAGGCATGCT
TAAAGGTATTACAGAAAAACAAGATTTATTGATTCACGCCGTAACTGGTGCGGGCAAAACCGAAATGATTTATCAATCTT
TGGCCAAAGTTATTGATAATGGTGGAAGTGTCTGCTTAGCGAGTCCACGGATTGATGTTTGTTTAGAACTTTATAAACGT
TTATCACGGGATTTTTCTTGCCCGATTACGCTTTTACACGGTGATTCTGAGCCGTATAAACGTTCTCCACTGGTAATTGC
AACGACCCATCAACTTTTAAAATTTTACCGAGCATTTGATTTATTAATCATCGACGAAGTTGATGCCTTTCCCTTTGTTG
ATAATAAAATGCTTTATCACGCGGTCAACCAATCCTTAAAAGATGATGGCGTTAAACTCTTTTTAACAGCGACTTCGACT
GATGAACTTGATAAAAAGGTGAAAAAAGGAGAGCTGACAAAGCTGCATTTGGCAAGACGTTTTCATGCCAATCCTTTGGT
AGTCCCCAAAATGGTTTGGTTAAGCAAAGTGCTAATCGCAATGAAAAAGAAAAAACTTCCTCCTAAACTAATCTCTCTTT
TAAAAAAACAAAGGCAAAGTCAATTTCCGCTTCTTATCTTTTTTCCGAATATTGAACAAGGTAGAGAATTTACAAGTATC
TTACAAACCACTTTTCCAGATGAAAGGATAGGATTTGTATCAAGTAAAACTGAAAATCGTCTGGAATTGGTAGAAGAATT
TAGACAAGGAAAATTAACCATACTAGTGACGACAACCATTCTAGAACGTGGGGTAACCTTTCCTTGTGTTGATGTTTTTG
TCCTACTTGCAAATCATAAATTGTACAGCAAAAGTGCACTTGTACAGATATCAGGACGAGTTGGACGAGCAGCCGAGAGA
CCGACAGGAGAGTTATTGTTCTTGCATGATGGCGTAACAAAAGCTATGAAAAAAGCTATTTCTGAAATAAAAGAAATGAA
TCACAAAGGAGGATTTTAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(96-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

61.593

98.843

0.609
  comFA/cflA Streptococcus pneumoniae D39

61.593

98.843

0.609
  comFA/cflA Streptococcus pneumoniae R6

61.593

98.843

0.609
  comFA/cflA Streptococcus pneumoniae TIGR4

61.593

98.843

0.609
  comFA/cflA Streptococcus mitis NCTC 12261

61.358

98.843

0.606
  comFA/cflA Streptococcus mitis SK321

60.89

98.843

0.602
  comFA Lactococcus lactis subsp. cremoris KW2

49.764

98.148

0.488
  comFA Latilactobacillus sakei subsp. sakei 23K

38.303

100

0.387

Multiple sequence alignment