Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GOM46_RS01350 Genome accession   NZ_CP046525
Coordinates   264592..265419 (+) Length   275 a.a.
NCBI ID   WP_006150172.1    Uniprot ID   F5VZ53
Organism   Streptococcus infantis strain SO     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 259592..270419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS01315 (GOM46_01300) asnA 259675..260667 (+) 993 WP_006150123.1 aspartate--ammonia ligase -
  GOM46_RS01320 (GOM46_01305) rsmD 260728..261267 (+) 540 WP_006150185.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  GOM46_RS01325 (GOM46_01310) coaD 261257..261745 (+) 489 WP_235083734.1 pantetheine-phosphate adenylyltransferase -
  GOM46_RS01330 (GOM46_01315) sepM 261729..262766 (+) 1038 WP_235083735.1 SepM family pheromone-processing serine protease Regulator
  GOM46_RS01335 (GOM46_01320) - 262824..263054 (+) 231 WP_033685906.1 DUF1146 family protein -
  GOM46_RS01340 (GOM46_01325) murA 263079..264365 (+) 1287 WP_235083736.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GOM46_RS01345 (GOM46_01330) - 264358..264546 (+) 189 WP_006150292.1 DNA-directed RNA polymerase subunit beta -
  GOM46_RS01350 (GOM46_01335) endA 264592..265419 (+) 828 WP_006150172.1 DNA/RNA non-specific endonuclease Machinery gene
  GOM46_RS01355 (GOM46_01340) - 265538..266869 (+) 1332 WP_006150075.1 hemolysin family protein -
  GOM46_RS01365 (GOM46_01350) amiA 267205..269184 (+) 1980 WP_006150231.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 275 a.a.        Molecular weight: 30051.66 Da        Isoelectric Point: 9.8125

>NTDB_id=405043 GOM46_RS01350 WP_006150172.1 264592..265419(+) (endA) [Streptococcus infantis strain SO]
MNKKTRQALIGLLIFLLLTAGSYYIKKMQASNNTPQTQVTQKSQSSDTPSQELAESVLTDSVKKQIKGTIEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGGETVPTVANALMSKATRQYKDREETGNGSTSWTPAGWHQVKNLKGSYNHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQARAEDSTGQNYYEGLVRKALDKNKRVRYRVTLLYATEEDLVPSASQIE
AKSSDGELEFNVVIPNVQKGIRLDYRTGEVTVTKD

Nucleotide


Download         Length: 828 bp        

>NTDB_id=405043 GOM46_RS01350 WP_006150172.1 264592..265419(+) (endA) [Streptococcus infantis strain SO]
ATGAATAAAAAAACCAGACAGGCCCTCATAGGTCTCCTGATTTTTCTACTATTGACGGCAGGAAGTTACTACATTAAAAA
AATGCAGGCTTCCAATAATACACCACAAACACAAGTGACACAAAAATCCCAGTCATCCGACACTCCTAGTCAAGAATTGG
CAGAGAGTGTACTGACTGACTCGGTCAAAAAACAAATCAAGGGTACAATTGAGTGGAATGGAGCAGGAGCTTTTGTAGTT
AATGGAAACAAAACCAATCTAGATGCTAAGGTATCAAGTAAACCTTATGCTGATAATAAAACTAAAACTGTAGGAGGAGA
GACAGTTCCTACAGTAGCCAATGCTCTCATGTCAAAAGCAACTCGACAGTATAAGGATCGCGAAGAGACGGGTAATGGTT
CGACCTCTTGGACTCCAGCAGGCTGGCATCAGGTCAAGAACCTAAAAGGAAGTTATAATCACGCTGTAGATAGAGGACAT
TTATTAGGCTATGCCTTGATTGGTGGTCTAGATGGCTTTGATGCATCTACTAGTAATCCTAAAAACATCGCTGTACAAAC
AGCCTGGGCCAACCAAGCTCGCGCAGAAGATTCAACAGGACAAAACTACTATGAAGGTTTAGTTCGAAAAGCGCTAGATA
AGAATAAACGAGTGCGTTACCGCGTTACGCTACTGTATGCGACAGAAGAGGACCTAGTACCTTCTGCCTCTCAAATTGAA
GCAAAATCCTCTGACGGAGAATTGGAGTTTAATGTAGTAATTCCTAATGTTCAAAAGGGAATTCGGTTAGATTACCGAAC
AGGAGAAGTTACGGTTACAAAAGACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5VZ53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

83.577

99.636

0.833
  endA Streptococcus pneumoniae D39

83.577

99.636

0.833
  endA Streptococcus pneumoniae R6

83.577

99.636

0.833
  endA Streptococcus pneumoniae TIGR4

83.577

99.636

0.833

Multiple sequence alignment