Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GOM48_RS09580 Genome accession   NZ_CP046523
Coordinates   1906341..1907639 (-) Length   432 a.a.
NCBI ID   WP_235097551.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1901341..1912639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS09560 (GOM48_09495) - 1901662..1903635 (-) 1974 WP_235097547.1 DHH family phosphoesterase -
  GOM48_RS09565 (GOM48_09500) - 1903787..1904965 (-) 1179 WP_235098772.1 acetyl-CoA C-acetyltransferase -
  GOM48_RS09570 (GOM48_09505) hpf 1905054..1905602 (-) 549 WP_000599119.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  GOM48_RS09575 (GOM48_09510) comFC/cflB 1905682..1906344 (-) 663 WP_235097549.1 ComF family protein Machinery gene
  GOM48_RS09580 (GOM48_09515) comFA/cflA 1906341..1907639 (-) 1299 WP_235097551.1 DEAD/DEAH box helicase Machinery gene
  GOM48_RS09585 (GOM48_09520) - 1907696..1908331 (+) 636 WP_235097553.1 YigZ family protein -
  GOM48_RS09590 (GOM48_09525) - 1908346..1908789 (+) 444 WP_235097555.1 PH domain-containing protein -
  GOM48_RS09595 (GOM48_09530) cysK 1908886..1909812 (+) 927 WP_235097557.1 cysteine synthase A -
  GOM48_RS09600 (GOM48_09535) tsf 1909927..1910967 (-) 1041 WP_235097559.1 translation elongation factor Ts -
  GOM48_RS09605 (GOM48_09540) rpsB 1911047..1911826 (-) 780 WP_125423540.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49461.44 Da        Isoelectric Point: 8.3096

>NTDB_id=404951 GOM48_RS09580 WP_235097551.1 1906341..1907639(-) (comFA/cflA) [Streptococcus oralis strain SOD]
MKVNPNYLGRLFTEKELTKEECQMAVKLPAMRKEKGKLFCQRCNSSILEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVIDEGGAVCLASPRIDVCLELYKR
LQNDFACEIALLHGESEPYFRTPLVVATTHQLLKFHHAFDLLIVDEVDAFPYVDNPMLYYAVNQCVKVEGVKIFLTATST
DELDKRVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRYLDKSQLSPKLKSSIEKQRRTGYPLLIFASEIKKGEKLKEI
LQEQFPNENIGFVSSVTENRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNTSIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=404951 GOM48_RS09580 WP_235097551.1 1906341..1907639(-) (comFA/cflA) [Streptococcus oralis strain SOD]
ATGAAAGTAAATCCAAACTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTAAAGAAGAATGTCAGATGGCCGTGAA
ACTGCCAGCAATGAGAAAAGAGAAGGGAAAACTTTTCTGTCAACGGTGTAATAGTAGCATTCTAGAAGAATGGTATTTGC
CTATTGGTGCTTACTACTGCAGGGAGTGCTTGCTGATGAAACGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCACAG
GAGGATTTTCCTAAGCAAGACGTCCTCAAATGGCGTGGTCAGTTAACACCTTTTCAAGAAAAAGTTTCAGAGGGACTTCT
TCAAGCGGTAGACAAGCAAGAGCCAACCTTGGTTCACGCTGTAACAGGAGCGGGAAAGACAGAGATGATTTATCAAGTTG
TGGCTAAAGTGATTGATGAAGGTGGTGCAGTTTGTTTAGCCAGCCCTCGAATAGATGTTTGCTTGGAGTTATATAAGCGA
CTGCAGAATGACTTTGCTTGTGAGATAGCACTACTTCATGGTGAGTCAGAACCCTATTTTCGAACACCACTAGTTGTTGC
AACGACTCACCAGCTATTAAAATTTCATCATGCTTTTGATTTGCTGATAGTGGACGAAGTAGATGCCTTTCCTTATGTTG
ACAACCCTATGCTTTACTACGCTGTAAACCAATGTGTAAAGGTGGAGGGGGTGAAGATATTCCTTACGGCGACTTCTACA
GATGAGTTAGATAAGAGGGTTCGCACAGGAGAATTAAAACGATTGAGCTTGCCAAGACGATTTCATGGAAATCCATTGAT
TATTCCAAAGCCAGTTTGGTTATCGGATTTTAATCGTTATTTAGATAAGAGTCAGTTGTCACCTAAGTTAAAGAGCTCCA
TTGAGAAGCAGAGAAGAACAGGTTATCCCTTGTTAATCTTTGCATCAGAAATTAAAAAAGGCGAGAAACTAAAAGAAATA
TTGCAGGAACAGTTTCCAAATGAAAATATCGGCTTTGTTTCCTCTGTCACAGAAAATCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAGTTGACGATACTGATCAGTACGACAATTTTAGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGCTTGATTCAGATTGGTGGGCGAGTTGGGCGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATACTTCCATCAAAAAGGCAATCAAGGAAATCAAGCAGATGAA
CAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-167)

Helicase conserved C-terminal domain (Helicase_C)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.741

100

0.907
  comFA/cflA Streptococcus pneumoniae Rx1

90.046

100

0.9
  comFA/cflA Streptococcus pneumoniae D39

90.046

100

0.9
  comFA/cflA Streptococcus pneumoniae R6

90.046

100

0.9
  comFA/cflA Streptococcus mitis SK321

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae TIGR4

89.815

100

0.898
  comFA Lactococcus lactis subsp. cremoris KW2

51.834

94.676

0.491
  comFA Latilactobacillus sakei subsp. sakei 23K

38.337

100

0.384

Multiple sequence alignment