Detailed information NTG0404942

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GOM48_RS08505
• Genome accession: NZ_CP046523
• Coordinates: 1690468..1691478 (-)
• Length: 336 a.a.
• NCBI ID: WP_038804599.1
• Uniprot ID: A0A3R9K0P0
• Organism: Streptococcus oralis strain SOD
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1685468..1696478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS08480 (GOM48_08420)	-	1685688..1686902 (-)	1215	WP_235097130.1	pyridoxal phosphate-dependent aminotransferase	-
GOM48_RS08485 (GOM48_08425)	-	1687047..1687346 (-)	300	WP_235097131.1	hypothetical protein	-
GOM48_RS08490 (GOM48_08430)	-	1687513..1687965 (+)	453	WP_000079159.1	universal stress protein	-
GOM48_RS08495 (GOM48_08435)	-	1688001..1689386 (-)	1386	WP_235097132.1	Cof-type HAD-IIB family hydrolase	-
GOM48_RS08500 (GOM48_08440)	-	1689452..1690414 (+)	963	WP_235097133.1	asparaginase	-
GOM48_RS08505 (GOM48_08445)	ccpA	1690468..1691478 (-)	1011	WP_038804599.1	catabolite control protein A	Regulator
GOM48_RS08510 (GOM48_08450)	-	1691688..1692005 (+)	318	WP_125394886.1	DUF960 domain-containing protein	-
GOM48_RS08515 (GOM48_08455)	folK	1692052..1692864 (-)	813	WP_235097134.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
GOM48_RS08520 (GOM48_08460)	folE	1692907..1693461 (-)	555	WP_235097135.1	GTP cyclohydrolase I FolE	-
GOM48_RS08525 (GOM48_08465)	-	1693442..1694761 (-)	1320	WP_235097136.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
GOM48_RS08530 (GOM48_08470)	folP	1694763..1695707 (-)	945	WP_235097137.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37215.31 Da
• Isoelectric Point: 5.4980

>NTDB_id=404942 GOM48_RS08505 WP_038804599.1 1690468..1691478(-) (ccpA) [Streptococcus oralis strain SOD]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDIEHQLPS
VNIDYKQATIDAVTHLLQENEKIAFVSGPLVDDINGKIRLIGYKEALKKAGIPYSEGLVFESKYSYNDGYALAERLVSSQ
ATAAVVTGDELAAGVLNGLADHGISVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=404942 GOM48_RS08505 WP_038804599.1 1690468..1691478(-) (ccpA) [Streptococcus oralis strain SOD]
ATGAACACAGATGATACAGTAACGATTTATGATGTTGCCCGTGAAGCTGGGGTTTCAATGGCAACTGTTAGCCGTGTAGT
GAATGGCAATAAGAACGTCAAAGAGAATACTCGTAAAAAAGTTCTAGAGGTGATTGATCGTCTTGACTACCGTCCAAATG
CGGTAGCGCGTGGCTTGGCCAGCAAGAAAACCACGACAGTTGGTGTTGTGATTCCAAATATCACCAATGGCTATTTTTCA
ACCCTAGCCAAGGGGATTGATGATATTGCAGAGATGTATAAGTACAATATCGTCCTAGCCAACAGTGATGAAGATGATGA
AAAAGAAGTTTCAGTAGTTAATACTCTCTTTTCAAAACAGGTTGACGGGATCATTTTTATGGGTTATCACTTGACTGAAA
AGATTCGTTCAGAATTTTCTCGATCTCGGACACCAGTTGTCCTTGCAGGAACAGTGGATATCGAACACCAGTTGCCAAGT
GTTAATATTGACTACAAACAAGCAACGATTGATGCAGTAACTCATTTGCTTCAGGAAAATGAAAAGATTGCCTTTGTCAG
TGGGCCACTTGTTGATGATATCAACGGCAAAATTCGATTGATTGGTTACAAGGAAGCATTGAAAAAGGCAGGAATCCCTT
ATAGCGAGGGCTTGGTATTTGAGTCTAAATACAGCTATAATGATGGCTATGCCTTGGCAGAACGCTTGGTTTCTTCACAG
GCTACAGCTGCAGTTGTGACAGGTGATGAATTGGCTGCGGGTGTGTTAAATGGCTTGGCAGATCACGGTATTTCTGTACC
GGAAGAGTTTGAAATCATTACGACAGATGATTCTCAAATTGCACGATTCACTCGTCCAAACTTAACGACAATTGCTCAAC
CTCTATACGACCTTGGTGCTATCAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTTTTGCCTCACGGTTTGACAGAACGTCGTTCGACACGAAAACGCAAGTAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A3R9K0P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	92.262	100	0.923
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568