Detailed information NTG0404043

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: GNT55_RS26340
• Genome accession: NZ_CP046404
• Coordinates: 5587870..5589207 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain SE5416
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5582870..5594207

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNT55_RS26315 (GNT55_26290)	pgeF	5583013..5583741 (-)	729	WP_003123393.1	peptidoglycan editing factor PgeF	-
GNT55_RS26320 (GNT55_26295)	rluD	5583738..5584700 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
GNT55_RS26325 (GNT55_26300)	-	5584846..5585871 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
GNT55_RS26330 (GNT55_26305)	-	5586028..5586273 (+)	246	WP_003102591.1	PP0621 family protein	-
GNT55_RS26335 (GNT55_26310)	pilS	5586263..5587855 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
GNT55_RS26340 (GNT55_26315)	pilR	5587870..5589207 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
GNT55_RS26345 (GNT55_26320)	thiO	5589253..5590347 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
GNT55_RS26350 (GNT55_26325)	-	5590482..5590991 (+)	510	WP_017002065.1	Tfp pilus assembly protein FimT/FimU	-
GNT55_RS26355 (GNT55_26330)	-	5591097..5591603 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
GNT55_RS26360 (GNT55_26335)	pilV	5591594..5592151 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
GNT55_RS26365 (GNT55_26340)	pilW	5592148..5592972 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
GNT55_RS26370 (GNT55_26345)	pilX	5592969..5593556 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=404043 GNT55_RS26340 WP_003094694.1 5587870..5589207(+) (pilR) [Pseudomonas aeruginosa strain SE5416]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=404043 GNT55_RS26340 WP_003094694.1 5587870..5589207(+) (pilR) [Pseudomonas aeruginosa strain SE5416]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGCCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384