Detailed information NTG0403975

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: GNT44_RS27630
• Genome accession: NZ_CP046402
• Coordinates: 5827574..5828911 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain SE5331
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5822574..5833911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNT44_RS27605 (GNT44_27585)	pgeF	5822717..5823445 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
GNT44_RS27610 (GNT44_27590)	rluD	5823442..5824404 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
GNT44_RS27615 (GNT44_27595)	-	5824550..5825575 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
GNT44_RS27620 (GNT44_27600)	-	5825732..5825977 (+)	246	WP_014603563.1	PP0621 family protein	-
GNT44_RS27625 (GNT44_27605)	pilS	5825967..5827559 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
GNT44_RS27630 (GNT44_27610)	pilR	5827574..5828911 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
GNT44_RS27635 (GNT44_27615)	thiO	5828957..5830051 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
GNT44_RS27640 (GNT44_27620)	-	5830186..5830695 (+)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
GNT44_RS27645 (GNT44_27625)	-	5830801..5831307 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
GNT44_RS27650 (GNT44_27630)	pilV	5831298..5831855 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
GNT44_RS27655 (GNT44_27635)	pilW	5831852..5832676 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
GNT44_RS27660 (GNT44_27640)	pilX	5832673..5833260 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=403975 GNT44_RS27630 WP_003094694.1 5827574..5828911(+) (pilR) [Pseudomonas aeruginosa strain SE5331]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=403975 GNT44_RS27630 WP_003094694.1 5827574..5828911(+) (pilR) [Pseudomonas aeruginosa strain SE5331]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384