Detailed information NTG0040382

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPYALAB49_RS02280
• Genome accession: NC_017596
• Coordinates: 427773..428774 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes Alab49
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 422773..433774

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYALAB49_RS02255 (SPYALAB49_000460)	-	423447..424130 (-)	684	WP_014635345.1	DUF969 domain-containing protein	-
SPYALAB49_RS02260 (SPYALAB49_000461)	-	424341..425267 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
SPYALAB49_RS02265 (SPYALAB49_000462)	-	425412..425789 (-)	378	WP_002985686.1	VOC family protein	-
SPYALAB49_RS02270 (SPYALAB49_000463)	-	425800..426465 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
SPYALAB49_RS02275 (SPYALAB49_000464)	-	426514..427599 (-)	1086	WP_011054264.1	aminopeptidase P family protein	-
SPYALAB49_RS02280 (SPYALAB49_000465)	ccpA	427773..428774 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
SPYALAB49_RS02285 (SPYALAB49_000466)	-	428905..429903 (+)	999	WP_002994184.1	glycosyltransferase family 4 protein	-
SPYALAB49_RS02290 (SPYALAB49_000467)	-	429905..431239 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
SPYALAB49_RS02295 (SPYALAB49_000468)	thrS	431661..433604 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=40382 SPYALAB49_RS02280 WP_002985680.1 427773..428774(+) (ccpA) [Streptococcus pyogenes Alab49]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=40382 SPYALAB49_RS02280 WP_002985680.1 427773..428774(+) (ccpA) [Streptococcus pyogenes Alab49]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559