Detailed information NTG0403696

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: GL187_RS08975
• Genome accession: NZ_CP046379
• Coordinates: 1775563..1776630 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain 563
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1770563..1781630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS08950 (GL187_09075)	treR	1770941..1771651 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
GL187_RS08955 (GL187_09080)	-	1771684..1772487 (-)	804	WP_024477717.1	ABC transporter ATP-binding protein	-
GL187_RS08960 (GL187_09085)	-	1772500..1773393 (-)	894	WP_024477718.1	ABC transporter permease	-
GL187_RS08965 (GL187_09090)	-	1773405..1774007 (-)	603	WP_024477719.1	ABC transporter substrate-binding protein	-
GL187_RS08970 (GL187_09095)	amiF	1774626..1775552 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
GL187_RS08975 (GL187_09100)	amiE	1775563..1776630 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
GL187_RS08980 (GL187_09105)	amiD	1776639..1777565 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
GL187_RS08985 (GL187_09110)	amiC	1777565..1779061 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
GL187_RS08990 (GL187_09115)	amiA3	1779128..1781107 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=403696 GL187_RS08975 WP_000159556.1 1775563..1776630(-) (amiE) [Streptococcus pneumoniae strain 563]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=403696 GL187_RS08975 WP_000159556.1 1775563..1776630(-) (amiE) [Streptococcus pneumoniae strain 563]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541