Detailed information NTG0403348

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: GL188_RS08865
• Genome accession: NZ_CP046359
• Coordinates: 1756528..1757595 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain 573
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1751528..1762595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL188_RS08840 (GL188_09000)	treR	1751906..1752616 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
GL188_RS08845 (GL188_09005)	-	1752649..1753452 (-)	804	WP_024477717.1	ABC transporter ATP-binding protein	-
GL188_RS08850 (GL188_09010)	-	1753465..1754358 (-)	894	WP_024477718.1	ABC transporter permease	-
GL188_RS08855 (GL188_09015)	-	1754370..1754972 (-)	603	WP_024477719.1	ABC transporter substrate-binding protein	-
GL188_RS08860 (GL188_09020)	amiF	1755591..1756517 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
GL188_RS08865 (GL188_09025)	amiE	1756528..1757595 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
GL188_RS08870 (GL188_09030)	amiD	1757604..1758530 (-)	927	WP_197120262.1	oligopeptide ABC transporter permease OppC	Regulator
GL188_RS08875 (GL188_09035)	amiC	1758530..1760026 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
GL188_RS08880 (GL188_09040)	amiA3	1760093..1762072 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=403348 GL188_RS08865 WP_000159556.1 1756528..1757595(-) (amiE) [Streptococcus pneumoniae strain 573]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=403348 GL188_RS08865 WP_000159556.1 1756528..1757595(-) (amiE) [Streptococcus pneumoniae strain 573]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541