Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   GL188_RS08840 Genome accession   NZ_CP046359
Coordinates   1751906..1752616 (+) Length   236 a.a.
NCBI ID   WP_000760673.1    Uniprot ID   A0A062WVH4
Organism   Streptococcus pneumoniae strain 573     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1746906..1757616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL188_RS08825 (GL188_08985) - 1747447..1747695 (-) 249 WP_000364990.1 YneF family protein -
  GL188_RS08830 (GL188_08990) treC 1747951..1749576 (-) 1626 WP_016398080.1 alpha,alpha-phosphotrehalase -
  GL188_RS08835 (GL188_08995) treP 1749754..1751721 (-) 1968 WP_024477716.1 PTS system trehalose-specific EIIBC component -
  GL188_RS08840 (GL188_09000) treR 1751906..1752616 (+) 711 WP_000760673.1 trehalose operon repressor Regulator
  GL188_RS08845 (GL188_09005) - 1752649..1753452 (-) 804 WP_024477717.1 ABC transporter ATP-binding protein -
  GL188_RS08850 (GL188_09010) - 1753465..1754358 (-) 894 WP_024477718.1 ABC transporter permease -
  GL188_RS08855 (GL188_09015) - 1754370..1754972 (-) 603 WP_024477719.1 ABC transporter substrate-binding protein -
  GL188_RS08860 (GL188_09020) amiF 1755591..1756517 (-) 927 WP_001291293.1 ATP-binding cassette domain-containing protein Regulator
  GL188_RS08865 (GL188_09025) amiE 1756528..1757595 (-) 1068 WP_000159556.1 ABC transporter ATP-binding protein Regulator

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27607.78 Da        Isoelectric Point: 8.9698

>NTDB_id=403346 GL188_RS08840 WP_000760673.1 1751906..1752616(+) (treR) [Streptococcus pneumoniae strain 573]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide


Download         Length: 711 bp        

>NTDB_id=403346 GL188_RS08840 WP_000760673.1 1751906..1752616(+) (treR) [Streptococcus pneumoniae strain 573]
ATGAAAAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTTCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACGGACTATCTGGATATGGAACTAATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAAAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(89-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WVH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

59.322

100

0.593

Multiple sequence alignment