Detailed information NTG0403279

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL186_RS09535
• Genome accession: NZ_CP046358
• Coordinates: 1865997..1867007 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 566
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1860997..1872007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL186_RS09510 (GL186_09675)	-	1861062..1862276 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
GL186_RS09515 (GL186_09680)	-	1862432..1862725 (-)	294	WP_000977366.1	hypothetical protein	-
GL186_RS09520 (GL186_09685)	-	1862888..1863340 (+)	453	WP_000079148.1	universal stress protein	-
GL186_RS09525 (GL186_09690)	-	1863375..1864763 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL186_RS09530 (GL186_09695)	-	1864829..1865791 (+)	963	WP_001124777.1	asparaginase	-
GL186_RS09535 (GL186_09700)	ccpA	1865997..1867007 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL186_RS09540 (GL186_09705)	-	1867432..1868031 (-)	600	WP_000866719.1	response regulator transcription factor	-
GL186_RS09545 (GL186_09710)	-	1868033..1869130 (-)	1098	WP_000893546.1	sensor histidine kinase	-
GL186_RS09550 (GL186_09715)	-	1869130..1869867 (-)	738	WP_000832834.1	ABC transporter permease	-
GL186_RS09555 (GL186_09720)	-	1869869..1870753 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL186_RS09560 (GL186_09725)	-	1870740..1870934 (-)	195	WP_000820180.1	hypothetical protein	-
GL186_RS09565 (GL186_09730)	-	1870931..1871137 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403279 GL186_RS09535 WP_000990607.1 1865997..1867007(-) (ccpA) [Streptococcus pneumoniae strain 566]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403279 GL186_RS09535 WP_000990607.1 1865997..1867007(-) (ccpA) [Streptococcus pneumoniae strain 566]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568