Detailed information NTG0403212

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: GL185_RS09480
• Genome accession: NZ_CP046357
• Coordinates: 1859120..1861099 (+)
• Length: 659 a.a.
• NCBI ID: WP_000742232.1
• Uniprot ID: A0A0E8SZP8
• Organism: Streptococcus pneumoniae strain 525
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1857192..1858538	1859120..1861099	flank	582

Gene organization within MGE regions

Location: 1857192..1861099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL185_RS09475 (GL185_09620)	-	1857192..1858538 (+)	1347	WP_024477720.1	IS1380-like element ISSpn5 family transposase	-
GL185_RS09480 (GL185_09625)	amiA3	1859120..1861099 (+)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 659 a.a.
• Molecular weight: 72435.35 Da
• Isoelectric Point: 4.6642

>NTDB_id=403212 GL185_RS09480 WP_000742232.1 1859120..1861099(+) (amiA3) [Streptococcus pneumoniae strain 525]
MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTADPETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAP
AVAEDWEVSKDGLTYTYKIRKGVKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNGPFLLKGLTAKSSVEFVKNEQYW
DKENVHLDTINLAYYDGSDQESLERNFTSGAYSYARLYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTS
KTTDSEKVATKKALLNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLPAYGDEWKG
VNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYISRIQSFKQSVETVLGVENVVVDIQQMTSDE
FLNITYYAANASSEDWDVSGGVSWGPDYQDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETS
DLNVRYEKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQDKAVTKEEYEKAREKWL
KEKAESNEKAQKELASHVK

Nucleotide

• Length: 1980 bp

>NTDB_id=403212 GL185_RS09480 WP_000742232.1 1859120..1861099(+) (amiA3) [Streptococcus pneumoniae strain 525]
ATGAAAAAAAATCGTGTATTTGCTACAGCAGGTCTTGTTTTATTAGCAGCAGGTGTACTTGCAGCATGCAGTTCTTCAAA
ATCATCTGATTCATCAGCCCCTAAAGCTTATGGCTATGTTTATACAGCAGACCCAGAAACCTTGGACTACCTGATTTCAA
GTAAAAATAGTACAACAGTAGTGACTTCAAATGGGATTGATGGTTTATTCACTAACGATAATTACGGTAATCTTGCTCCT
GCAGTTGCAGAGGATTGGGAAGTCTCTAAGGATGGTTTGACCTACACTTATAAGATTCGTAAAGGGGTTAAATGGTTTAC
CTCTGATGGAGAAGAATATGCAGAGGTGACGGCTAAAGATTTCGTGAACGGTTTAAAACACGCAGCAGATAAAAAATCAG
AAGCTATGTATTTAGCTGAAAATTCGGTTAAAGGCTTGGCAGATTATCTATCAGGAACTTCAACAGATTTTTCAACAGTT
GGTGTCAAGGCGGTTGATGATTATACGTTACAATACACTTTGAACCAGCCTGAACCGTTCTGGAACTCTAAGTTGACCTA
TTCTATTTTCTGGCCTCTGAATGAAGAATTCGAAACATCAAAAGGAAGCGATTTTGCTAAACCAACAGATCCGACATCCT
TGCTTTATAATGGTCCATTCTTGTTGAAAGGGTTGACTGCAAAATCTTCTGTAGAGTTTGTAAAAAATGAGCAATATTGG
GATAAAGAAAATGTCCACCTAGATACTATCAATCTAGCTTACTATGATGGATCAGATCAGGAGTCGCTAGAGCGTAACTT
CACTAGTGGAGCCTATAGTTATGCCCGTCTTTACCCTACCAGCTCCAACTATTCTAAGGTTGCAGAAGAATACAAGGACA
ATATCTATTACACACAATCAGGCTCTGGGATTGCTGGTCTGGGTGTGAATATTGATCGCCAAAGTTACAACTATACTTCT
AAAACTACAGATTCAGAGAAAGTAGCTACTAAGAAGGCATTGCTTAACAAAGATTTCCGTCAAGCCTTGAATTTTGCTCT
TGATCGCTCAGCTTACTCAGCTCAAATCAATGGTAAAGATGGAGCAGCTTTAGCAGTTCGTAATTTATTTGTAAAACCAG
ACTTTGTTTCAGCTGGTGAGAAGACCTTTGGTGATTTAGTCGCTGCTCAACTTCCTGCTTATGGTGATGAGTGGAAAGGT
GTGAATTTAGCTGATGGGCAGGATGGTTTATTCAATGCTGACAAGGCCAAGGCAGAGTTTGCGAAAGCTAAGAAAGCTTT
AGAAGCAGACGGCGTTCAGTTTCCTATTCATCTGGACGTTCCAGTAGACCAAGCATCAAAAAACTATATATCTCGTATTC
AGTCCTTTAAACAATCTGTAGAAACAGTTCTTGGTGTTGAAAATGTCGTTGTTGATATTCAACAAATGACAAGTGATGAA
TTCCTTAATATTACTTACTATGCTGCCAATGCTTCATCTGAGGATTGGGATGTATCGGGAGGAGTTTCATGGGGGCCAGA
CTATCAAGACCCATCTACTTACCTGGATATTTTAAAAACAACTAGCAGTGAAACTACAAAAACATATTTAGGATTTGATA
ATCCAAATAGCCCTTCAGTAGTTCAAGTTGGTTTGAAAGAATACGATAAATTAGTTGATGAAGCTGCCAAAGAGACAAGC
GACTTGAATGTCCGTTATGAAAAATATGCAGCGGCTCAAGCATGGTTGACAGATAGTTCACTCTTTATTCCTGCTATGGC
TTCTTCTGGTGCAGCACCAGTGCTTTCACGAATTGTTCCATTTACTGGAGCTTCTGCGCAAACAGGCTCTAAGGGGTCAG
ATGTTTACTTCAAATATTTGAAATTACAAGATAAAGCGGTGACTAAGGAAGAGTATGAAAAAGCTCGTGAAAAATGGTTG
AAAGAAAAAGCTGAATCAAATGAGAAAGCTCAAAAAGAATTGGCAAGTCATGTGAAGTAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (78-522)

3D structure

• AlphaFold DB: A0A0E8SZP8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	66.818	100	0.669
amiA3	Streptococcus thermophilus LMG 18311	66.667	100	0.668
amiA	Streptococcus salivarius strain HSISS4	66.768	100	0.668