Detailed information NTG0403204

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL185_RS08865
• Genome accession: NZ_CP046357
• Coordinates: 1757544..1758554 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 525
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1752544..1763554

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL185_RS08835 (GL185_08990)	-	1753414..1753620 (+)	207	WP_000503437.1	hypothetical protein	-
GL185_RS08840 (GL185_08995)	-	1753617..1753811 (+)	195	WP_000820180.1	hypothetical protein	-
GL185_RS08845 (GL185_09000)	-	1753798..1754682 (+)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL185_RS08850 (GL185_09005)	-	1754684..1755421 (+)	738	WP_000832834.1	ABC transporter permease	-
GL185_RS08855 (GL185_09010)	-	1755421..1756518 (+)	1098	WP_000893546.1	sensor histidine kinase	-
GL185_RS08860 (GL185_09015)	-	1756520..1757119 (+)	600	WP_000866719.1	response regulator transcription factor	-
GL185_RS08865 (GL185_09020)	ccpA	1757544..1758554 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL185_RS08870 (GL185_09025)	-	1758760..1759722 (-)	963	WP_001124777.1	asparaginase	-
GL185_RS08875 (GL185_09030)	-	1759788..1761176 (+)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL185_RS08880 (GL185_09035)	-	1761211..1761663 (-)	453	WP_000079148.1	universal stress protein	-
GL185_RS08885 (GL185_09040)	-	1761826..1762119 (+)	294	WP_000977366.1	hypothetical protein	-
GL185_RS08890 (GL185_09045)	-	1762275..1763501 (+)	1227	WP_197097759.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403204 GL185_RS08865 WP_000990607.1 1757544..1758554(+) (ccpA) [Streptococcus pneumoniae strain 525]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403204 GL185_RS08865 WP_000990607.1 1757544..1758554(+) (ccpA) [Streptococcus pneumoniae strain 525]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568