Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   GL183_RS03870 Genome accession   NZ_CP046355
Coordinates   722460..724418 (+) Length   652 a.a.
NCBI ID   WP_000748881.1    Uniprot ID   A0A0F7YA13
Organism   Streptococcus pneumoniae strain 475     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 717460..729418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL183_RS03845 (GL183_03870) - 717597..718109 (+) 513 WP_000892251.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -
  GL183_RS03850 (GL183_03875) - 718093..718742 (+) 650 Protein_712 DUF1803 domain-containing protein -
  GL183_RS03855 (GL183_03880) - 718843..719037 (+) 195 WP_000051195.1 CsbD family protein -
  GL183_RS03860 (GL183_03885) - 719083..720528 (-) 1446 WP_000590289.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  GL183_RS03865 (GL183_03890) - 720634..722256 (+) 1623 WP_000017793.1 polysaccharide biosynthesis protein -
  GL183_RS03870 (GL183_03895) amiA 722460..724418 (+) 1959 WP_000748881.1 peptide ABC transporter substrate-binding protein Regulator
  GL183_RS03875 (GL183_03900) - 724590..725546 (+) 957 WP_024477842.1 ABC transporter ATP-binding protein -
  GL183_RS03880 (GL183_03905) - 725550..726272 (+) 723 WP_050201235.1 ATP-binding cassette domain-containing protein -
  GL183_RS03885 (GL183_03910) - 726429..727523 (+) 1095 WP_061649952.1 cystathionine gamma-synthase -
  GL183_RS03890 (GL183_03915) - 727531..728697 (+) 1167 WP_024477840.1 MalY/PatB family protein -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72571.96 Da        Isoelectric Point: 4.9478

>NTDB_id=403041 GL183_RS03870 WP_000748881.1 722460..724418(+) (amiA) [Streptococcus pneumoniae strain 475]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=403041 GL183_RS03870 WP_000748881.1 722460..724418(+) (amiA) [Streptococcus pneumoniae strain 475]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACGGCGTCAAAAACCTACAACTATGTTTATTCAAGTGATCCATCTAGCTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCCT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAGTACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGAGTTCTACAAAATCTTGGACTAGAGCCTGGAGAAGCCAATG
ACAAGGCTAAGGAAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAGCAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YA13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.422

100

0.566
  amiA3 Streptococcus thermophilus LMD-9

55.878

100

0.561
  amiA3 Streptococcus thermophilus LMG 18311

55.725

100

0.56

Multiple sequence alignment