Detailed information NTG0403017

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL183_RS01360
• Genome accession: NZ_CP046355
• Coordinates: 258036..259046 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 475
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 253036..264046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL183_RS01330 (GL183_01355)	-	253906..254112 (+)	207	WP_000503437.1	hypothetical protein	-
GL183_RS01335 (GL183_01360)	-	254109..254303 (+)	195	WP_000820180.1	hypothetical protein	-
GL183_RS01340 (GL183_01365)	-	254290..255174 (+)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL183_RS01345 (GL183_01370)	-	255176..255913 (+)	738	WP_000832834.1	ABC transporter permease	-
GL183_RS01350 (GL183_01375)	-	255913..257010 (+)	1098	WP_000893546.1	sensor histidine kinase	-
GL183_RS01355 (GL183_01380)	-	257012..257611 (+)	600	WP_000866719.1	response regulator transcription factor	-
GL183_RS01360 (GL183_01385)	ccpA	258036..259046 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL183_RS01365 (GL183_01390)	-	259252..260214 (-)	963	WP_001124777.1	asparaginase	-
GL183_RS01370 (GL183_01395)	-	260280..261668 (+)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL183_RS01375 (GL183_01400)	-	261703..262155 (-)	453	WP_000079148.1	universal stress protein	-
GL183_RS01380 (GL183_01405)	-	262318..262611 (+)	294	WP_000977366.1	hypothetical protein	-
GL183_RS01385 (GL183_01410)	-	262767..263993 (+)	1227	WP_197097759.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403017 GL183_RS01360 WP_000990607.1 258036..259046(+) (ccpA) [Streptococcus pneumoniae strain 475]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403017 GL183_RS01360 WP_000990607.1 258036..259046(+) (ccpA) [Streptococcus pneumoniae strain 475]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568