Detailed information NTG0402783

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FOB92_RS01190
• Genome accession: NZ_CP046335
• Coordinates: 238210..239220 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus mitis strain FDAARGOS_684
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 233210..244220

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB92_RS01165 (FOB92_01165)	folP	233806..234780 (+)	975	WP_000240964.1	dihydropteroate synthase	-
FOB92_RS01170 (FOB92_01170)	-	234782..236104 (+)	1323	WP_000658435.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
FOB92_RS01175 (FOB92_01175)	folE	236085..236639 (+)	555	WP_000380931.1	GTP cyclohydrolase I FolE	-
FOB92_RS01180 (FOB92_01180)	folK	236682..237494 (+)	813	WP_000372493.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
FOB92_RS01185 (FOB92_01185)	-	237655..237972 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
FOB92_RS01190 (FOB92_01190)	ccpA	238210..239220 (+)	1011	WP_001090627.1	catabolite control protein A	Regulator
FOB92_RS01195 (FOB92_01195)	-	239274..240236 (-)	963	WP_001124765.1	asparaginase	-
FOB92_RS01200 (FOB92_01200)	-	240302..241693 (+)	1392	WP_078228369.1	Cof-type HAD-IIB family hydrolase	-
FOB92_RS01205 (FOB92_01205)	-	241909..242361 (-)	453	WP_000079148.1	universal stress protein	-
FOB92_RS01210 (FOB92_01210)	-	242523..242825 (+)	303	WP_000977176.1	hypothetical protein	-
FOB92_RS01215 (FOB92_01215)	-	242982..244196 (+)	1215	WP_000666474.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=402783 FOB92_RS01190 WP_001090627.1 238210..239220(+) (ccpA) [Streptococcus mitis strain FDAARGOS_684]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=402783 FOB92_RS01190 WP_001090627.1 238210..239220(+) (ccpA) [Streptococcus mitis strain FDAARGOS_684]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGTAAAAAAGTGCTTGAGGTGATTGACCGTTTGGATTACCGTCCAAATG
CAGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATACCAAATATTACCAATGGTTATTTCTCA
ACGCTTGCCAAAGGGATTGATGATATTGCTGAAATGTACAAGTATAATATCGTTCTTGCTAATAGTGATGAGGATGATGA
TAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACACCAACTTCCAAGT
GTTAATATTGACTACAAACAAGCTACGATTGATGCAGTGACCTACCTTGCTAAAGAAAATGAGCGCATTGCTTTCGTAAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAGTCTAAATACACTTATGAAGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAGCTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTATCAGTACC
AGAAGAATTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGGGCCATCAGTATGCGTATGTTGACCAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGGAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571